SCHEMBL201885

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5758856	0.83	HDAC1 (0.52)	HDAC1HDAC8HDAC6NPC1ALDH1A1
	SCHEMBL1696000	0.83	HDAC1 (0.49)	HDAC1HDAC8HDAC6NPC1ALDH1A1
	SCHEMBL5760187	0.81	HDAC1 (0.50)	HDAC1HDAC8HDAC6NPC1ALDH1A1
	SCHEMBL5761606	0.78	HDAC1 (0.48)	HDAC1HDAC8HDAC6NPC1ALDH1A1
	SCHEMBL5759818	0.72	KMT2A (0.50)	HDAC1HDAC8HDAC6NPC1ALDH1A1
	SCHEMBL10247601	0.72	HDAC1 (0.45)	HDAC1HDAC8HDAC6NPC1ALDH1A1
	SCHEMBL202789	0.72	DRD2 (0.54)	HDAC1HDAC8HDAC6ALDH1A1KMT2A
	SCHEMBL5761247	0.70	HDAC1 (0.46)	HDAC1HDAC8HDAC6NPC1ALDH1A1
	SCHEMBL16884255	0.70	EPHX2 (0.45)	HDAC1HDAC8HDAC6ALDH1A1KDM4E
	SCHEMBL16573559	0.70	MAPT (0.46)	HDAC1HDAC8HDAC6NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.