Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | GLA | P06280 | 1/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | CASP1 | P29466 | 1/20 | 0.54 |
| ▸ | BRCA1 | P38398 | 1/20 | 0.54 |
| ▸ | CASP7 | P55210 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6001320 | 0.80 | ALDH1A1 (0.59) | LMNAKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL5584152 | 0.79 | KDM4E (0.65) | LMNAKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL1896215 | 0.77 | LMNA (0.66) | LMNAKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL241548 | 0.73 | FLT3 (0.71) | LMNAKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL30402838 | 0.70 | KDM4E (1.00) | LMNAKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL1390692 | 0.70 | KDM4E (1.00) | LMNAKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL4507247 | 0.70 | KDM4E (0.74) | LMNAKDM4EALDH1A1GAAHSD17B10 | |
| SCHEMBL15920417 | 0.70 | POLH (0.58) | KDM4EALDH1A1HSD17B10HPGDSMN1; SMN2 | |
| SCHEMBL430311 | 0.70 | CYP1A2 (0.59) | KDM4EALDH1A1HSD17B10HPGDCASP1 | |
| SCHEMBL30323818 | 0.70 | CYP1A2 (0.59) | KDM4EALDH1A1HSD17B10HPGDCASP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018096401-A1 | NEW NAPHTHO[2,3-B]FURAN DERIVATIVES | BAN HITOSHI (JP) | 2018-05-31 | — | — | WO | disclosed |