SCHEMBL2018959

SCHEMBL2018959

c1ccc(-c2ccc(P(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 2/20 0.71
TDP1 Q9NUW8 2/20 0.71
ESR1 P03372 3/20 0.59
ESR2 Q92731 3/20 0.59
ALDH1A1 P00352 2/20 0.53
TAAR1 Q96RJ0 2/20 0.46
CYP1A2 P05177 2/20 0.46
MAPK1 P28482 1/20 0.46
HSD17B10 Q99714 1/20 0.46
MMP3 P08254 1/20 0.46
BCL2L1 Q07817 1/20 0.46
CA1 P00915 2/20 0.42
CA2 P00918 2/20 0.42
CA12 O43570 1/20 0.42
CA9 Q16790 1/20 0.42
KDM4E B2RXH2 1/20 0.41
GAA P10253 1/20 0.41
MGLL Q99685 1/20 0.40
KIF11 P52732 1/20 0.40
NOTUM Q6P988 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30388209 1.00 CYP3A4 (0.71) CYP3A4TDP1ESR1ESR2ALDH1A1
SCHEMBL19262009 1.00 CYP3A4 (0.71) CYP3A4TDP1ESR1ESR2ALDH1A1
SCHEMBL6292055 0.97 CYP3A4 (0.65) CYP3A4TDP1ESR1ESR2ALDH1A1
SCHEMBL2024694 0.97 CYP3A4 (0.75) CYP3A4TDP1ESR1ESR2ALDH1A1
Biphenyl SCHEMBL6633071 0.94 CYP3A4 (0.80) CYP3A4TDP1ESR1ESR2ALDH1A1
Biphenyl SCHEMBL4383765 0.91 CYP3A4 (0.75) CYP3A4TDP1ESR1ESR2ALDH1A1
Biphenyl SCHEMBL7874731 0.91 CYP3A4 (0.75) CYP3A4TDP1ESR1ESR2ALDH1A1
Biphenyl SCHEMBL4381705 0.91 CYP3A4 (0.75) CYP3A4TDP1ESR1ESR2ALDH1A1
Biphenyl SCHEMBL27510461 0.91 CYP3A4 (0.75) CYP3A4TDP1ESR1ESR2ALDH1A1
SCHEMBL17808449 0.89 CYP3A4 (0.63) CYP3A4TDP1ESR1ESR2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109970789-B Preparation method of triarylphosphine compound 大连理工大学 2021-05-07 CN disclosed
CN-109970789-A A kind of preparation method of triaryl phosphine compound 大连理工大学 2019-07-05 CN disclosed
WO-2019103155-A1 EUROPIUM COMPLEX 東ソー株式会社 2019-05-31 WO disclosed
US-8563465-B2 Hydrogen storage material JX NIPPON OIL & ENERGY CORPORATION (JP) 2013-10-22 US disclosed
US-20110160456-A1 HYDROGEN STORAGE MATERIAL JX NIPPON OIL & ENERGY CORPORATION (JP) 2011-06-30 US disclosed
US-4472319-A Preparation of unsaturated nitriles using a surfactant PHILLIPS PETROLEUM COMPANY (US) 1984-09-18 US disclosed
US-4255352-A TANK REACTORS IN SERIES PHILLIPS PETROLEUM COMPANY (US) 1981-03-10 US disclosed
US-4218394-A FROM UNSATURATED NITRILES AND OLEFINS PHILLIPS PETROLEUM COMPANY (US) 1980-08-19 US disclosed
US-4217303-A UNSATURATED HYDROCARBON, ADDUCT, UNSATURATED DINITRILE, BY-PRODUCT INHIBITION PHILLIPS PETROLEUM COMPANY (US) 1980-08-12 US disclosed
US-4200586-A Inhibiting the carbon-carbon double bond isomerization of substituted or unsubstituted hydrocarbon compounds PHILLIPS PETROLEUM COMPANY (US) 1980-04-29 US disclosed
US-3996262-A Method of promoting the reaction of unsaturated nitriles with olefins to produce unsaturated nitriles of increased carbon number PHILLIPS PETROLEUM COMPANY (US) 1976-12-07 US disclosed
US-3985786-A REACTING AN OLEFINICALLY UNSATURATED NITRILE, AN OLEFINIC HYDROCARBON AND THEIR MONOADDUCT IN WATER PHILLIPS PETROLEUM COMPANY (US) 1976-10-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110160456-A1 HYDROGEN STORAGE MATERIAL HVCN1, HIRA, FTH1 CYP3A4 3826/4885TDP1 3890/4885ESR1 1352/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.