Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 13/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | THRB | P10828 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.55 |
| ▸ | APEX1 | P27695 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.55 |
| ▸ | RECQL | P46063 | 1/20 | 0.55 |
| ▸ | CASP6 | P55212 | 1/20 | 0.55 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Resazurin SCHEMBL29370889 | 0.87 | KMT2A (0.70) | APPMEN1POLBKMT2AKDM4E | |
| Resazurin SCHEMBL6338 | 0.87 | KMT2A (0.70) | APPMEN1POLBKMT2AKDM4E | |
| Resazurin SCHEMBL8665938 | 0.87 | KMT2A (0.70) | APPMEN1POLBKMT2AKDM4E | |
| Resazurin SCHEMBL29456662 | 0.86 | KMT2A (0.68) | APPMEN1POLBKMT2AKDM4E | |
| Resazurin SCHEMBL21823760 | 0.86 | KMT2A (0.68) | APPMEN1POLBKMT2AKDM4E | |
| Resazurin SCHEMBL5492813 | 0.86 | KMT2A (0.68) | APPMEN1POLBKMT2AKDM4E | |
| Resazurin SCHEMBL10937342 | 0.86 | KMT2A (0.68) | APPMEN1POLBKMT2AKDM4E | |
| Resazurin SCHEMBL272629 | 0.86 | KMT2A (0.72) | APPMEN1POLBKMT2AKDM4E | |
| SCHEMBL8066 | 0.84 | APP (1.00) | APPMEN1POLBKMT2ACYP1A2 | |
| Resazurin SCHEMBL10638468 | 0.83 | KMT2A (0.65) | APPMEN1POLBKMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3765076-A1 | METABOLIC ENZYME ACTIVITY AND DISULFIDE BOND REDUCTION DURING PROTEIN PRODUCTION | Bristol-Myers Squibb Company (US) | 2021-01-20 | — | — | EP | disclosed |
| WO-2019178489-A1 | METABOLIC ENZYME ACTIVITY AND DISULFIDE BOND REDUCTION DURING PROTEIN PRODUCTION | BRISTOL-MYERS SQUIBB COMPANY (US) | 2019-09-19 | — | — | WO | disclosed |
| WO-2018098402-A1 | METHODS, COMPOSITIONS, AND KITS FOR DETECTING BACTERIOPHAGE IN A SAMPLE | SONANUTECH INC. (US) | 2018-05-31 | — | — | WO | disclosed |