Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Resazurin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB known ✓ | P10828 | 1/20 | 0.72 |
| ▸ | ESR2 known ✓ | Q92731 | 2/20 | 0.38 |
| ▸ | CA12 known ✓ | O43570 | 2/20 | 0.35 |
| ▸ | CA1 known ✓ | P00915 | 2/20 | 0.35 |
| ▸ | CA2 known ✓ | P00918 | 2/20 | 0.35 |
| ▸ | XDH known ✓ | P47989 | 1/20 | 0.35 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.72 |
| ▸ | MEN1 | O00255 | 6/20 | 0.72 |
| ▸ | POLB | P06746 | 4/20 | 0.72 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.72 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.72 |
| ▸ | CASP6 | P55212 | 2/20 | 0.72 |
| ▸ | GAA | P10253 | 2/20 | 0.72 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.72 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.72 |
| ▸ | PKM | P14618 | 2/20 | 0.72 |
| ▸ | MAPT | P10636 | 2/20 | 0.72 |
| ▸ | APEX1 | P27695 | 1/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Resazurin SCHEMBL29370889 | 0.99 | KMT2A (0.70) | KMT2AMEN1POLBKDM4EMAPK1 | |
| Resazurin SCHEMBL6338 | 0.99 | KMT2A (0.70) | KMT2AMEN1POLBKDM4EMAPK1 | |
| Resazurin SCHEMBL8665938 | 0.99 | KMT2A (0.70) | KMT2AMEN1POLBKDM4EMAPK1 | |
| Resazurin SCHEMBL10937342 | 0.97 | KMT2A (0.68) | KMT2AMEN1POLBKDM4EMAPK1 | |
| Resazurin SCHEMBL21823760 | 0.97 | KMT2A (0.68) | KMT2AMEN1POLBKDM4EMAPK1 | |
| Resazurin SCHEMBL29456662 | 0.97 | KMT2A (0.68) | KMT2AMEN1POLBKDM4EMAPK1 | |
| Resazurin SCHEMBL5492813 | 0.97 | KMT2A (0.68) | KMT2AMEN1POLBKDM4EMAPK1 | |
| Resazurin SCHEMBL10638468 | 0.94 | KMT2A (0.65) | KMT2AMEN1POLBKDM4EMAPK1 | |
| Resazurin SCHEMBL20190032 | 0.86 | APP (0.71) | KMT2AMEN1POLBKDM4EMAPK1 | |
| Resazurin SCHEMBL29375844 | 0.84 | KDM4E (1.00) | KMT2AMEN1POLBKDM4EMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 655 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116626001-B | Method for measuring adsorption rate of sulfate reducing bacteria on coal surface based on fluorescence spectrophotometry | 中国矿业大学 | 2024-04-05 | — | — | CN | claimed |
| CN-116626001-A | Method for measuring adsorption rate of sulfate reducing bacteria on coal surface based on fluorescence spectrophotometry | 中国矿业大学 | 2023-08-22 | — | — | CN | claimed |
| CN-111307775-A | Method for detecting PBMC activity under in-vitro 3D culture condition by applying resazurin reagent | 郑州鲲鹏健康科技有限公司 | 2020-06-19 | — | — | CN | claimed |
| US-20200080979-A1 | METHOD AND DEVICES FOR THE SPECTROPHOTOMETRIC DETERMINATION OF RESIDUAL PHASE TRANSFER CATALYST IN A PET RADIOPHARMACEUTICAL DOSE | UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION | 2020-03-12 | — | — | US | claimed |
| US-20130217765-A1 | MULTIFUNCTIONAL NANOCONJUGATES AND USES THEREOF | WISYS TECHNOLOGY FOUNDATION, INC. | 2013-08-22 | — | — | US | claimed |
| CN-100379877-C | Method of monitoring biofouling in membrane separation systems | NALCO CORP (US) | 2008-04-09 | — | — | CN | claimed |
| CN-1685060-A | Method of monitoring biofouling in membrane separation systems | NALCO CORP (US) | 2005-10-19 | — | — | CN | claimed |
| JP-2046291-A | — | — | None | — | — | JP | disclosed |
| JP-62019099-A | — | — | None | — | — | JP | disclosed |
| JP-6209766-A | — | — | None | — | — | JP | disclosed |
| JP-9124076-A | — | — | None | — | — | JP | disclosed |
| US-20240240226-A1 | FLUOROGENIC ASSAY FOR RAPID SCREENING OF BACTERIAL BETA-LACTAMASE ACTIVITY | UNIV LELAND STANFORD JUNIOR (US) | 2024-07-18 | — | — | US | disclosed |
| US-12036234-B2 | Heparin conjugated to collagen-binding peptides for targeting to biological and synthetic tissues | NORTHWESTERN UNIVERSITY (US) | 2024-07-16 | — | — | US | disclosed |
| US-5035998-A | Hydrolase substrates | BOEHRINGER MANNHEIM GMBH (DE) | 1991-07-30 | — | — | US | disclosed |
| JP-H0246291-A | RECOMBINANT DNA CONTAINING GENE OF BETA-GALACTOSE | AMANO PHARMACEUT CO LTD | 1990-02-15 | — | — | JP | disclosed |
| US-4900822-A | New hydrolase substrates | BOEHRINGER MANNHEIM GMBH (DE) | 1990-02-13 | — | — | US | disclosed |
| US-4716222-A | CHROMOGENS, SPECTROPHOTOMETRY | HOECHST AKTIENGESELLSCHAFT (DE) | 1987-12-29 | — | — | US | disclosed |
| JP-S6219099-A | JUDGMENT OF QUALITY OF MALT OR THE LIKE | SAPPORO BREWERIES LTD | 1987-01-27 | — | — | JP | disclosed |
| US-4540666-A | Methane fermentation | MATSUSHITA ELECTRIC INDUSTRIAL COMPANY, LIMITED (JP) | 1985-09-10 | — | — | US | disclosed |
| JP-H00246291-A | — | — | 0001-01-01 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130217765-A1 | MULTIFUNCTIONAL NANOCONJUGATES AND USES THEREOF | CD47, CLTA, CD63 | THRB 3490/4885ESR2 2655/4885CA12 48/4885 |
| US-12036234-B2 | Heparin conjugated to collagen-binding peptides for targeting to biological and synthetic tissues | COL14A1, MATR3, COL2A1 | THRB 2421/4885ESR2 2966/4885CA12 1201/4885 |
| US-20240240226-A1 | FLUOROGENIC ASSAY FOR RAPID SCREENING OF BACTERIAL BETA-LACTAMASE ACTIVITY | CDA, CMBL, CTSF | THRB 3420/4885ESR2 1654/4885CA12 2306/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.