Resazurin

Resazurin

SCHEMBL21823760

O=c1ccc2[n+]([O-])c3ccc(O)cc3oc-2c1.[H+]

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.68
MEN1 O00255 6/20 0.68
POLB P06746 4/20 0.68
KDM4E B2RXH2 4/20 0.68
MAPK1 P28482 2/20 0.68
L3MBTL1 Q9Y468 2/20 0.68
CASP6 P55212 2/20 0.68
GAA P10253 2/20 0.68
MCL1 Q07820 2/20 0.68
TDP1 Q9NUW8 2/20 0.68
PKM P14618 2/20 0.68
MAPT P10636 2/20 0.68
THRB P10828 1/20 0.68
APEX1 P27695 1/20 0.68
CTNNB1 P35222 1/20 0.68
RECQL P46063 1/20 0.68
NPSR1 Q6W5P4 1/20 0.68
RXFP1 Q9HBX9 1/20 0.68
APP P05067 1/20 0.46
USP2 O75604 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Resazurin SCHEMBL29370889 0.99 KMT2A (0.70) KMT2AMEN1POLBKDM4EMAPK1
Resazurin SCHEMBL6338 0.99 KMT2A (0.70) KMT2AMEN1POLBKDM4EMAPK1
Resazurin SCHEMBL8665938 0.99 KMT2A (0.70) KMT2AMEN1POLBKDM4EMAPK1
Resazurin SCHEMBL5492813 0.97 KMT2A (0.68) KMT2AMEN1POLBKDM4EMAPK1
Resazurin SCHEMBL272629 0.97 KMT2A (0.72) KMT2AMEN1POLBKDM4EMAPK1
Resazurin SCHEMBL29456662 0.97 KMT2A (0.68) KMT2AMEN1POLBKDM4EMAPK1
Resazurin SCHEMBL10937342 0.97 KMT2A (0.68) KMT2AMEN1POLBKDM4EMAPK1
Resazurin SCHEMBL10638468 0.94 KMT2A (0.65) KMT2AMEN1POLBKDM4EMAPK1
Resazurin SCHEMBL20190032 0.86 APP (0.71) KMT2AMEN1POLBKDM4EMAPK1
SCHEMBL17921280 0.82 KMT2A (0.49) KMT2AMEN1POLBKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20210402182-A1 TREATMENT DELIVERY SYSTEM WearOptimo Pty Ltd (AU) 2021-12-30 US disclosed
US-20210386373-A1 ANALYTE DETECTION SYSTEM WearOptimo Pty Ltd (AU) 2021-12-16 US disclosed
US-20210338158-A1 MEASUREMENT SYSTEM WearOptimo Pty Ltd (AU) 2021-11-04 US disclosed
EP-3860453-A1 MEASUREMENT SYSTEM Wearoptimo Pty Ltd (AU) 2021-08-11 EP disclosed
WO-2020069570-A1 ANALYTE DETECTION SYSTEM WearOptimo Pty Ltd (AU) 2020-04-09 WO disclosed
WO-2020069568-A1 TREATMENT DELIVERY SYSTEM WearOptimo Pty Ltd (AU) 2020-04-09 WO disclosed
WO-2020069565-A1 MEASUREMENT SYSTEM WearOptimo Pty Ltd (AU) 2020-04-09 WO disclosed