Resazurin

Resazurin

SCHEMBL5492813

O=c1ccc2[n+]([O-])c3ccc(O)cc3oc-2c1.[NaH]

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 7/20 0.68
MEN1 O00255 6/20 0.68
POLB P06746 4/20 0.68
KDM4E B2RXH2 4/20 0.68
MAPK1 P28482 2/20 0.68
L3MBTL1 Q9Y468 2/20 0.68
CASP6 P55212 2/20 0.68
GAA P10253 2/20 0.68
MCL1 Q07820 2/20 0.68
TDP1 Q9NUW8 2/20 0.68
PKM P14618 2/20 0.68
MAPT P10636 2/20 0.68
THRB P10828 1/20 0.68
APEX1 P27695 1/20 0.68
CTNNB1 P35222 1/20 0.68
RECQL P46063 1/20 0.68
NPSR1 Q6W5P4 1/20 0.68
RXFP1 Q9HBX9 1/20 0.68
APP P05067 1/20 0.46
USP2 O75604 3/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Resazurin SCHEMBL29370889 0.99 KMT2A (0.70) KMT2AMEN1POLBKDM4EMAPK1
Resazurin SCHEMBL6338 0.99 KMT2A (0.70) KMT2AMEN1POLBKDM4EMAPK1
Resazurin SCHEMBL8665938 0.99 KMT2A (0.70) KMT2AMEN1POLBKDM4EMAPK1
Resazurin SCHEMBL272629 0.97 KMT2A (0.72) KMT2AMEN1POLBKDM4EMAPK1
Resazurin SCHEMBL21823760 0.97 KMT2A (0.68) KMT2AMEN1POLBKDM4EMAPK1
Resazurin SCHEMBL29456662 0.97 KMT2A (0.68) KMT2AMEN1POLBKDM4EMAPK1
Resazurin SCHEMBL10937342 0.97 KMT2A (0.68) KMT2AMEN1POLBKDM4EMAPK1
Resazurin SCHEMBL10638468 0.94 KMT2A (0.65) KMT2AMEN1POLBKDM4EMAPK1
Resazurin SCHEMBL20190032 0.86 APP (0.71) KMT2AMEN1POLBKDM4EMAPK1
SCHEMBL17921280 0.82 KMT2A (0.49) KMT2AMEN1POLBKDM4EMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112912491-A Assays for cell-based therapies or treatments 加利福尼亚大学董事会 2021-06-04 CN claimed
US-20210139445-A1 Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, Display Device, and Lighting Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2021-05-13 US claimed
CN-118304321-A Composition for inhibiting glucosyltransferase activity as well as preparation method and application thereof 武汉简为医疗科技有限公司 2024-07-09 CN disclosed
EP-4225931-A1 OXYGEN-INSENSITIVE ELECTROCHEMICAL BIOSENSOR AND METHODS OF USE THEREOF Trividia Health, Inc. (US) 2023-08-16 EP disclosed
US-20220112536-A1 OXYGEN-INSENSITIVE ELECTROCHEMICAL BIOSENSOR AND METHODS OF USE THEREOF TRIVIDIA HEALTH, INC. 2022-04-14 US disclosed
US-20210208130-A1 ASSAYS FOR CELL-BASED THERAPIES OR TREATMENTS UNIV CALIFORNIA (US) 2021-07-08 US disclosed
CN-112912491-A Assays for cell-based therapies or treatments 加利福尼亚大学董事会 2021-06-04 CN disclosed
US-20200080979-A1 METHOD AND DEVICES FOR THE SPECTROPHOTOMETRIC DETERMINATION OF RESIDUAL PHASE TRANSFER CATALYST IN A PET RADIOPHARMACEUTICAL DOSE UNIVERSITY OF TENNESSEE RESEARCH FOUNDATION 2020-03-12 US disclosed
US-20140255984-A1 MICRO-ORGANISM THREAT DETECTION ZYZEBA TESTING LIMITED (NZ) 2014-09-11 US disclosed
WO-2012177150-A1 MICRO-ORGANISM THREAT DETECTION ZYZEBA TESTING LIMITED (NZ) 2012-12-27 WO disclosed
EP-0927353-B1 DETECTION OF MICROORGANISMS SBM LTD (NZ) 2007-05-09 EP disclosed
EP-0927353-A4 DETECTION OF MICROORGANISMS SIMMONS MAXINE HELEN (NZ) 2001-09-12 EP disclosed
EP-0927353-A2 DETECTION OF MICROORGANISMS Simmons, Maxine Helen (NZ) 1999-07-07 EP disclosed
WO-1998011250-A2 DETECTION OF MICROORGANISMS SIMMONS MAXINE HELEN (NZ) 1998-03-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210139445-A1 Organic Compound, Light-Emitting Device, Light-Emitting Apparatus, Electronic Device, Display Device, and Lighting Device DDT, SLC43A1, SLCO2A1 KMT2A 2717/4885MEN1 3747/4885POLB 4206/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.