Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26691228 | 0.86 | HSD11B1 (0.33) | HSD11B1 | |
| SCHEMBL24342357 | 0.83 | OPRM1 (0.38) | HSD11B1 | |
| SCHEMBL9278288 | 0.79 | KCNQ2 (0.31) | — | |
| SCHEMBL16306651 | 0.77 | KDM4E (0.34) | HSD11B1 | |
| SCHEMBL26455588 | 0.77 | CYP2D6 (0.37) | — | |
| SCHEMBL23875331 | 0.76 | — | — | |
| SCHEMBL12665794 | 0.76 | — | — | |
| SCHEMBL12666963 | 0.76 | DRD2 (0.34) | HSD11B1 | |
| SCHEMBL24842172 | 0.75 | CYP2D6 (0.36) | — | |
| SCHEMBL24316187 | 0.74 | KDM4E (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9981922-B2 | KDM1A inhibitors for the treatment of disease | IMAGO BIOSCIENCES, INC. (US) | 2018-05-29 | — | — | US | disclosed |