Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HRH2 | P25021 | 5/20 | 0.46 |
| ▸ | HRH1 | P35367 | 5/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.43 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.40 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.40 |
| ▸ | GPR183 | P32249 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17557995 | 0.86 | GLA (0.48) | GLAHRH2HRH1L3MBTL1MEN1 | |
| SCHEMBL12259096 | 0.81 | GLA (0.54) | GLAL3MBTL1MEN1KMT2ATDP1 | |
| SCHEMBL24880677 | 0.81 | GLA (0.49) | GLAHRH2HRH1TSHRSMN1; SMN2 | |
| SCHEMBL17167936 | 0.80 | GNAI3 (0.65) | HRH2HRH1L3MBTL1MEN1KMT2A | |
| SCHEMBL5856719 | 0.80 | SIGMAR1 (0.55) | GLAHRH2HRH1TSHRSMN1; SMN2 | |
| SCHEMBL17558012 | 0.79 | GLA (0.57) | GLAHRH2HRH1L3MBTL1MEN1 | |
| SCHEMBL17558014 | 0.79 | GLA (0.54) | GLAHRH2HRH1L3MBTL1MEN1 | |
| SCHEMBL12846943 | 0.78 | HRH2 (0.56) | HRH2HRH1ALDH1A1GPR183 | |
| SCHEMBL15781651 | 0.78 | PAOX (0.44) | HRH2HRH1TSHRSMN1; SMN2 | |
| SCHEMBL24773181 | 0.78 | HRH2 (0.53) | HRH2HRH1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9980967-B1 | Method for overcoming drug resistance of EGFR mutation and cancerous stemness of human non-small cell lung carcinoma | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2018-05-29 | — | — | US | disclosed |