Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.42 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17558014 | 0.97 | GLA (0.54) | GLATSHREPHX1EPHX2HTR1A | |
| SCHEMBL17557990 | 0.96 | GLA (0.52) | GLATSHREPHX1EPHX2HTR1A | |
| SCHEMBL17557969 | 0.96 | GLA (0.52) | GLATSHREPHX1EPHX2HTR1A | |
| SCHEMBL17558008 | 0.96 | GLA (0.52) | GLATSHREPHX1EPHX2HTR1A | |
| SCHEMBL17557995 | 0.93 | GLA (0.48) | GLATSHREPHX1EPHX2HTR1A | |
| SCHEMBL14980458 | 0.82 | GLA (0.70) | GLATSHREPHX1EPHX2ATM | |
| SCHEMBL5605546 | 0.81 | HTR7 (0.49) | TSHRHTR1AHTR7ATMALDH1A1 | |
| SCHEMBL5856719 | 0.81 | SIGMAR1 (0.55) | GLATSHRHTR1AHTR7HRH2 | |
| SCHEMBL20193377 | 0.79 | GLA (0.49) | GLATSHREPHX1EPHX2HTR1A | |
| SCHEMBL11570934 | 0.79 | TSHR (0.58) | GLATSHRHTR1AALDH1A1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9512086-B2 | Compound for promoting apoptosis of cancer cells and a pharmaceutical composition containing the same and uses thereof | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2016-12-06 | — | — | US | disclosed |
| US-9512086-B2 | Compound for promoting apoptosis of cancer cells and a pharmaceutical composition containing the same and uses thereof | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2016-12-06 | — | — | US | disclosed |
| US-9512086-B2 | Compound for promoting apoptosis of cancer cells and a pharmaceutical composition containing the same and uses thereof | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2016-12-06 | — | — | US | disclosed |
| US-20160068495-A1 | COMPOUND FOR PROMOTING APOPTOSIS OF CANCER CELLS AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND USES THEREOF | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2016-03-10 | — | — | US | disclosed |
| US-20160068495-A1 | COMPOUND FOR PROMOTING APOPTOSIS OF CANCER CELLS AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND USES THEREOF | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2016-03-10 | — | — | US | disclosed |
| US-20160068495-A1 | COMPOUND FOR PROMOTING APOPTOSIS OF CANCER CELLS AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND USES THEREOF | NATIONAL CHIAO TUNG UNIVERSITY (TW) | 2016-03-10 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160068495-A1 | COMPOUND FOR PROMOTING APOPTOSIS OF CANCER CELLS AND A PHARMACEUTICAL COMPOSITION CONTAINING THE SAME AND USES THEREOF | BAX, BCL2, CASP3 | GLA 4516/4885TSHR 4780/4885EPHX1 3590/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.