Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20194130 | 0.74 | F2 (0.45) | — | |
| SCHEMBL282407 | 0.68 | ALOX5 (0.69) | ALOX5 | |
| SCHEMBL20194147 | 0.68 | — | — | |
| SCHEMBL20194156 | 0.68 | — | — | |
| SCHEMBL23864570 | 0.62 | ALDH1A1 (0.35) | ALOX5 | |
| SCHEMBL1440765 | 0.62 | MAPT (0.44) | ALOX5 | |
| SCHEMBL31633499 | 0.62 | GAA (0.61) | ALOX5 | |
| SCHEMBL2301531 | 0.62 | GAA (0.56) | ALOX5 | |
| SCHEMBL193418 | 0.62 | GAA (0.61) | ALOX5 | |
| SCHEMBL235212 | 0.62 | CA12 (0.46) | ALOX5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3054955-B1 | PYRROLOTRIAZINE KINASE INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2018-05-30 | — | — | EP | disclosed |