Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | RECQL | P46063 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | BLM | P54132 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | HSPD1 | P10809 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30476086 | 0.83 | MAOB (0.45) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL8280039 | 0.83 | MAOB (0.45) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL30925630 | 0.81 | KDM4E (0.61) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL3079582 | 0.81 | MAPT (0.49) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL416879 | 0.81 | KDM4E (0.61) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL26054237 | 0.80 | MAPT (0.48) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL30311840 | 0.80 | MAPT (0.48) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| SCHEMBL24180500 | 0.79 | ALDH1A1 (0.52) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| Hydrochloric Acid SCHEMBL6984724 | 0.79 | KMT2A (0.64) | MAPTALDH1A1KDM4ETDP1MEN1 | |
| Hydrochloric Acid SCHEMBL20639113 | 0.79 | MAPT (0.48) | MAPTALDH1A1KDM4ETDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 116 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024217557-A1 | SUBSTITUTED TETRAHYDROFURANS AS NAV1.8 INHIBITORS | 武汉人福创新药物研发中心有限公司 | 2024-10-24 | — | — | WO | disclosed |
| CN-118812519-A | Substituted tetrahydrofurans as Nav1.8 inhibitors | 武汉人福创新药物研发中心有限公司 | 2024-10-22 | — | — | CN | disclosed |
| US-20230357165-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-11-09 | — | — | US | disclosed |
| US-20230357165-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2023-11-09 | — | — | US | disclosed |
| US-20230303497-A1 | BENZYLAMINE OR BENZYL ALCOHOL DERIVATIVE AND USES THEREOF | CHENGDU HYPERWAY PHARMACEUTICALS CO., LTD (CN) | 2023-09-28 | — | — | US | disclosed |
| US-20230303497-A1 | BENZYLAMINE OR BENZYL ALCOHOL DERIVATIVE AND USES THEREOF | CHENGDU HYPERWAY PHARMACEUTICALS CO., LTD (CN) | 2023-09-28 | — | — | US | disclosed |
| US-20230303497-A1 | BENZYLAMINE OR BENZYL ALCOHOL DERIVATIVE AND USES THEREOF | CHENGDU HYPERWAY PHARMACEUTICALS CO., LTD (CN) | 2023-09-28 | — | — | US | disclosed |
| EP-4230618-A1 | BENZYLAMINE OR BENZYL ALCOHOL DERIVATIVE AND USE THEREOF | Chengdu Hyperway Pharmaceuticals Co., Ltd. (CN) | 2023-08-23 | — | — | EP | disclosed |
| EP-4230618-A1 | BENZYLAMINE OR BENZYL ALCOHOL DERIVATIVE AND USE THEREOF | Chengdu Hyperway Pharmaceuticals Co., Ltd. (CN) | 2023-08-23 | — | — | EP | disclosed |
| CN-114031518-B | Benzylamine or benzyl alcohol derivative and application thereof | 成都海博为药业有限公司 | 2023-08-18 | — | — | CN | disclosed |
| US-5360822-A | FOR TREATING URINARY INCONTINENCE IN ANIMALS AND HUMANS | NIPPON SHINYAKU CO. LTD. (JP) | 1994-11-01 | — | — | US | disclosed |
| EP-0538469-A1 | SULFONANILIDE DERIVATIVE AND MEDICINE | NIPPON SHINYAKU COMPANY, LIMITED (JP) | 1993-04-28 | — | — | EP | disclosed |
| US-4777175-A | (NAPHTHYRIDINE, QUINOLINE) CARBOXYLIC ACID | WARNER-LAMBERT COMPANY (US) | 1988-10-11 | — | — | US | disclosed |
| US-4771054-A | QUINOLINE CARBOXYLIC ACID | WARNER-LAMBERT COMPANY (US) | 1988-09-13 | — | — | US | disclosed |
| EP-0106489-B1 | ANTIBACTERIAL AGENTS | WARNER-LAMBERT COMPANY (US) | 1988-07-27 | — | — | EP | disclosed |
| US-4665079-A | QUINOLINE DERIVATIVES | WARNER-LAMBERT COMPANY (US) | 1987-05-12 | — | — | US | disclosed |
| US-4638067-A | NAPHTHYRIDINE AND QUINOLINE CARBOXYLIC ACIDS | WARNER-LAMBERT CO. (US) | 1987-01-20 | — | — | US | disclosed |
| EP-0153163-A2 | 7-Substituted-1-cyclopropyl-6,8-difluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic acids; 7-substituted-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxo-1,8-naphthyridine-3-carboxylic acids; their derivatives; and a process for preparing the compounds | WARNER-LAMBERT COMPANY (US) | 1985-08-28 | — | — | EP | disclosed |
| EP-0106489-A2 | Antibacterial agents | WARNER-LAMBERT COMPANY (US) | 1984-04-25 | — | — | EP | disclosed |
| US-4145364-A | PREPARATION OF FLUORINATED ANILINES | MERCK & CO., INC. (US) | 1979-03-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230357165-A1 | QUINAZOLINONES DERIVATIVES FOR TREATMENT OF NON-ALCOHOLIC FATTY LIVER DISEASE, PREPARATION AND USE THEREOF | ATG7, GOT1, LIPC | MAPT 2243/4885ALDH1A1 295/4885KDM4E 1291/4885 |
| US-20230303497-A1 | BENZYLAMINE OR BENZYL ALCOHOL DERIVATIVE AND USES THEREOF | SCN8A, SCN9A, SCN10A | MAPT 1923/4885ALDH1A1 1050/4885KDM4E 1134/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.