Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.40 |
| ▸ | HTR3B | O95264 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.40 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | HPGD | P15428 | 5/20 | 0.38 |
| ▸ | TSHR | P16473 | 3/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | MMP14 | P50281 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20183676 | 0.91 | KDM4E (0.44) | KDM4EHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL20183528 | 0.80 | KDM4E (0.48) | KDM4EALDH1A1MAPTPKMTSHR | |
| SCHEMBL22625650 | 0.79 | KDM4E (0.39) | KDM4EHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL20183585 | 0.79 | RORC (0.54) | KDM4EALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL20183851 | 0.78 | ALDH1A1 (0.41) | KDM4EHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL20183648 | 0.78 | ALDH1A1 (0.51) | KDM4EALDH1A1MAPTPKMKMT2A | |
| SCHEMBL20183697 | 0.78 | KDM4E (0.48) | KDM4EHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL21549574 | 0.77 | ALDH1A1 (0.38) | KDM4EALDH1A1MAPTKMT2AHPGD | |
| SCHEMBL21549568 | 0.77 | KDM4E (0.39) | KDM4EHTR3EHTR3BHTR3AHTR3D | |
| SCHEMBL20183587 | 0.76 | KDM4E (0.41) | KDM4EHTR3EHTR3BHTR3AHTR3D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327004-A1 | NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | Fujifilm Corporation (JP) | 2018-05-30 | — | — | EP | disclosed |