Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.37 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | REV1 | Q9UBZ9 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | MMP14 | P50281 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20354220 | 0.91 | NPSR1 (0.38) | ALDH1A1NPSR1MAPTLMNAPTGDR2 | |
| SCHEMBL23253818 | 0.80 | RAB9A (0.33) | ALDH1A1HTTKDM4EHPGDHSD17B10 | |
| SCHEMBL20183746 | 0.78 | KDM4E (0.42) | ALDH1A1NPSR1MAPTLMNARORC | |
| SCHEMBL20183585 | 0.77 | RORC (0.54) | ALDH1A1NPSR1MAPTLMNARORC | |
| SCHEMBL20195204 | 0.77 | KDM4E (0.41) | ALDH1A1MAPTLMNAHTTKDM4E | |
| SCHEMBL20183676 | 0.77 | KDM4E (0.44) | ALDH1A1MAPTHTTKDM4EMEN1 | |
| SCHEMBL20195102 | 0.75 | MAPT (0.43) | ALDH1A1NPSR1MAPTLMNAPTGDR2 | |
| SCHEMBL20183528 | 0.75 | KDM4E (0.48) | ALDH1A1MAPTKDM4EPOLBSMN1; SMN2 | |
| SCHEMBL20354307 | 0.74 | KDM4E (0.36) | ALDH1A1MAPTLMNAHTTKDM4E | |
| SCHEMBL20183795 | 0.74 | KDM4E (0.38) | ALDH1A1NPSR1MAPTLMNARORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3563851-A1 | ANTITUMOR AGENT AND BROMODOMAIN INHIBITOR | FUJIFILM Corporation (JP) | 2019-11-06 | — | — | EP | disclosed |