Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.39 |
| ▸ | PTGFR | P43088 | 1/20 | 0.39 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | CYP4F2 | P78329 | 2/20 | 0.39 |
| ▸ | CYP4A11 | Q02928 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL642197 | 0.84 | ALOX5 (0.54) | NPC1ALOX5PPARGPPARAMAOB | |
| SCHEMBL1205512 | 0.82 | CYP4F2 (0.52) | NPC1ALOX5PPARGPPARAMAOB | |
| SCHEMBL901475 | 0.81 | CYP4F2 (0.55) | NPC1ALOX5PPARGPPARAMAOB | |
| SCHEMBL23940698 | 0.77 | TAAR1 (0.47) | MAOB | |
| SCHEMBL11066194 | 0.74 | NPC1 (0.46) | NPC1ALOX5PPARGPPARAMAOB | |
| SCHEMBL2485584 | 0.72 | MAOB (0.58) | NPC1L3MBTL1MAOBLMNAGLA | |
| SCHEMBL15926259 | 0.72 | CYP1A2 (0.48) | ALOX5L3MBTL1 | |
| SCHEMBL17429242 | 0.72 | CA1 (0.62) | L3MBTL1LMNAGLAMEN1KMT2A | |
| SCHEMBL17431555 | 0.72 | CA1 (0.62) | L3MBTL1LMNAGLAMEN1KMT2A | |
| SCHEMBL9278298 | 0.72 | PPARA (0.49) | NPC1PPARGPPARAMAOBCYP4F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2729447-B1 | POSITIVE ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTOR | H LUNDBECK AS (DK) | 2018-05-30 | — | — | EP | disclosed |