Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 1/20 | 0.44 |
| ▸ | HRH2 | P25021 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.43 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.42 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20858813 | 0.92 | MAOA (0.44) | TAAR1SLC6A3MAOAMAOBHRH2 | |
| SCHEMBL27962880 | 0.77 | TAAR1 (0.44) | TAAR1SLC6A3MAOAMAOB | |
| SCHEMBL20195256 | 0.77 | NPC1 (0.45) | MAOB | |
| SCHEMBL16191177 | 0.75 | SLC6A3 (0.45) | TAAR1SLC6A3MAOAMAOBHRH2 | |
| SCHEMBL8031355 | 0.74 | MAOA (0.57) | TAAR1SLC6A3MAOAMAOBDRD2 | |
| SCHEMBL27904615 | 0.74 | MAOA (0.57) | TAAR1SLC6A3MAOAMAOBDRD2 | |
| SCHEMBL24317060 | 0.73 | SLC6A4 (0.40) | TAAR1SLC6A3SLC6A4CHRM3SLC6A2 | |
| SCHEMBL429765 | 0.73 | TAAR1 (0.63) | TAAR1SLC6A3DRD2SLC6A4 | |
| SCHEMBL3371633 | 0.72 | TAAR1 (0.74) | TAAR1SLC6A3DRD2SLC6A4 | |
| Ammonia Solution, Strong SCHEMBL6195952 | 0.71 | TAAR1 (0.61) | TAAR1SLC6A3DRD2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974419-A2 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | Zhejiang Ausun Pharmaceutical Co., Ltd. (CN) | 2022-03-30 | — | — | EP | disclosed |
| EP-3299364-B1 | NEBIVOLOL SYNTHESIS METHOD AND INTERMEDIATE COMPOUND THEREOF | ZHEJIANG AUSUN PHARMACEUTICAL CO LTD (CN) | 2021-10-20 | — | — | EP | disclosed |