Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 14/20 | 0.47 |
| ▸ | ACACA | Q13085 | 9/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.42 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.42 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.39 |
| ▸ | PI4KA | P42356 | 1/20 | 0.39 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.39 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.39 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31475048 | 0.86 | ACACB (0.46) | ACACBACACAALDH1A1PIK3CDPIK3CA | |
| SCHEMBL3929602 | 0.86 | ACACB (0.46) | ACACBACACAALDH1A1PIK3CDPIK3CA | |
| SCHEMBL20245192 | 0.84 | ACACB (0.46) | ACACBACACAALDH1A1PIK3CDPIK3CA | |
| SCHEMBL20237226 | 0.83 | ACACB (0.45) | ACACBACACAALDH1A1PIK3CDPIK3CA | |
| SCHEMBL6468241 | 0.80 | ALDH1A1 (0.46) | ACACBACACAALDH1A1PIK3CDPIK3CA | |
| SCHEMBL3229511 | 0.80 | NNMT (0.44) | ACACBCYP4F2CYP4A11PIK3CA | |
| SCHEMBL21994583 | 0.79 | ALDH1A1 (0.45) | ACACBACACAALDH1A1PIK3CDPIK3CA | |
| SCHEMBL21503513 | 0.79 | ACACB (0.46) | ACACBACACAALDH1A1PIK3CDPIK3CA | |
| SCHEMBL3939368 | 0.79 | ALDH1A1 (0.45) | ACACBACACAALDH1A1PIK3CDPIK3CA | |
| SCHEMBL29796918 | 0.79 | ALDH1A1 (0.45) | ACACBACACAALDH1A1PIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023125681-A1 | HETEROCYCLIC COMPOUNDS | BEIGENE, LTD. (KY) | 2023-07-06 | — | — | WO | disclosed |
| EP-2729447-B1 | POSITIVE ALLOSTERIC MODULATORS OF NICOTINIC ACETYLCHOLINE RECEPTOR | H LUNDBECK AS (DK) | 2018-05-30 | — | — | EP | disclosed |