Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | ACACB | O00763 | 12/20 | 0.44 |
| ▸ | ACACA | Q13085 | 7/20 | 0.44 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.40 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.40 |
| ▸ | MLNR | O43193 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6468241 | 0.83 | ALDH1A1 (0.46) | ALDH1A1ACACBACACAPIK3CDPIK3CA | |
| SCHEMBL7992559 | 0.81 | ALDH1A1 (0.45) | ALDH1A1ACACBACACAPIK3CDPIK3CA | |
| SCHEMBL3939368 | 0.81 | ALDH1A1 (0.45) | ALDH1A1ACACBACACAPIK3CDPIK3CA | |
| SCHEMBL3929602 | 0.81 | ACACB (0.46) | ALDH1A1ACACBACACAPIK3CDPIK3CA | |
| SCHEMBL31475048 | 0.81 | ACACB (0.46) | ALDH1A1ACACBACACAPIK3CDPIK3CA | |
| SCHEMBL31143209 | 0.81 | ALDH1A1 (0.45) | ALDH1A1ACACBACACAPIK3CDPIK3CA | |
| SCHEMBL29796918 | 0.81 | ALDH1A1 (0.45) | ALDH1A1ACACBACACAPIK3CDPIK3CA | |
| SCHEMBL21503513 | 0.81 | ACACB (0.46) | ALDH1A1ACACBACACAPIK3CDPIK3CA | |
| SCHEMBL26962241 | 0.81 | ALDH1A1 (0.45) | ALDH1A1ACACBACACAPIK3CDPIK3CA | |
| SCHEMBL20245192 | 0.80 | ACACB (0.46) | ALDH1A1ACACBACACAPIK3CDPIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230165252-A1 | ACTIVE COMPOUND COMBINATIONS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-06-01 | — | — | US | disclosed |
| US-20230054449-A1 | PYRIDAZINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2023-02-23 | — | — | US | disclosed |
| EP-3887362-A1 | PYRIDAZINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | Bayer Aktiengesellschaft (DE) | 2021-10-06 | — | — | EP | disclosed |
| WO-2020109391-A1 | PYRIDAZINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | BAYER AKTIENGESELLSCHAFT (DE) | 2020-06-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230165252-A1 | ACTIVE COMPOUND COMBINATIONS | CYP51A1, ERG28, BROX | ALDH1A1 2558/4885ACACB 2491/4885ACACA 2694/4885 |
| US-20230054449-A1 | PYRIDAZINE (THIO)AMIDES AS FUNGICIDAL COMPOUNDS | PNPO, TPMT, BLVRB | ALDH1A1 2740/4885ACACB 1924/4885ACACA 3133/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.