Known targets — ChEMBL curated mechanism
CACNA1CCACNA1DCACNA1FCACNA1SDPP4HTR1BHTR1D
The experimentally established mechanism targets of Benzoic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.78 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.78 |
| ▸ | DAO | P14920 | 1/20 | 0.78 |
| ▸ | CES2 | O00748 | 3/20 | 0.64 |
| ▸ | CES1 | P23141 | 3/20 | 0.64 |
| ▸ | SRD5A2 | P31213 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.58 |
| ▸ | CA12 | O43570 | 6/20 | 0.56 |
| ▸ | CA2 | P00918 | 6/20 | 0.56 |
| ▸ | CA14 | Q9ULX7 | 5/20 | 0.56 |
| ▸ | CA1 | P00915 | 5/20 | 0.56 |
| ▸ | CA9 | Q16790 | 5/20 | 0.56 |
| ▸ | CA4 | P22748 | 4/20 | 0.56 |
| ▸ | CA7 | P43166 | 4/20 | 0.56 |
| ▸ | CA6 | P23280 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HMGB1 | P09429 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzoic Acid SCHEMBL7669891 | 1.00 | TSHR (0.78) | TSHRNAPRTDAOCES2CES1 | |
| Benzophenone SCHEMBL28156135 | 0.93 | SRD5A2 (0.77) | TSHRNAPRTDAOCES2CES1 | |
| Benzoic Acid SCHEMBL2458489 | 0.88 | TSHR (1.00) | TSHRNAPRTDAOCES2CES1 | |
| Benzoic Acid SCHEMBL4591761 | 0.88 | TSHR (1.00) | TSHRNAPRTDAOCES2CES1 | |
| Benzoic Acid SCHEMBL160564 | 0.88 | TSHR (1.00) | TSHRNAPRTDAOCES2CES1 | |
| Benzoic Acid SCHEMBL3966600 | 0.88 | TSHR (1.00) | TSHRNAPRTDAOCES2CES1 | |
| Benzoic Acid SCHEMBL976149 | 0.88 | TSHR (1.00) | TSHRNAPRTDAOCES2CES1 | |
| Benzoic Acid SCHEMBL407365 | 0.88 | TSHR (1.00) | TSHRNAPRTDAOCES2CES1 | |
| Benzoic Acid SCHEMBL149318 | 0.88 | TSHR (1.00) | TSHRNAPRTDAOCES2CES1 | |
| Benzoic Acid SCHEMBL137419 | 0.88 | TSHR (1.00) | TSHRNAPRTDAOCES2CES1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119591769-A | Organic polymer carrier, Z-N catalyst, and preparation method and application thereof | 中国石油天然气股份有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-1990601-B | Composition, composition manufacturing method, thermosensitive adhesive material, and information recording material | RICOH CO LTD | 2010-12-15 | — | — | CN | claimed |
| US-4833023-A | CONTAINING SOILD PLASTICIZER | MITSUBISHI PAPER MILLS, LTD. (JP) | 1989-05-23 | — | — | US | claimed |
| CN-119591769-A | Organic polymer carrier, Z-N catalyst, and preparation method and application thereof | 中国石油天然气股份有限公司 | 2025-03-11 | — | — | CN | disclosed |
| US-20240392047-A1 | CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION WITH IMPROVED CATALYST PERFORMANCE | W.R. GRACE & CO.-CONN (US) | 2024-11-28 | — | — | US | disclosed |
| EP-4396243-A1 | CATALYST COMPONENT FOR PROPYLENE POLYMERIZATION WITH IMPROVED CATALYST PERFORMANCE | W.R. GRACE & CO.-CONN. (US) | 2024-07-10 | — | — | EP | disclosed |
| CN-118251425-A | Catalyst component for propylene polymerization with improved catalyst performance | 格雷斯公司 | 2024-06-25 | — | — | CN | disclosed |
| US-20240174776-A1 | SPHERICAL CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION | W.R. GRACE & CO.-CONN. (US) | 2024-05-30 | — | — | US | disclosed |
| US-11891460-B2 | Activated catalyst components for olefin polymerization | W. R. GRACE & CO.-CONN. (US) | 2024-02-06 | — | — | US | disclosed |
| EP-4308615-A1 | SPHERICAL CATALYST COMPONENTS FOR OLEFIN POLYMERIZATION | W. R. Grace & Co.-Conn (US) | 2024-01-24 | — | — | EP | disclosed |
| CN-117355546-A | Spherical catalyst component for olefin polymerization | 格雷斯公司 | 2024-01-05 | — | — | CN | disclosed |
| EP-1440888-A1 | Method for issuing a label with thermosensitive adhesive | Ricoh Company (JP) | 2004-07-28 | — | — | EP | disclosed |
| EP-0699543-B1 | Printing paper | SONY CORP (JP) | 1999-12-01 | — | — | EP | disclosed |
| US-5635441-A | SHEET SUBSTRATE HAVING DYE RECEIVING LAYER OF CROSSLINKED COATING OBTAINED BY CURING MIXTURE OF BUTYRAL RESIN, VINYLPHENOLIC RESIN, POLYISOCYANATE; STORAGE STABLE IMAGES | SONY CORPORATION (JP) | 1997-06-03 | — | — | US | disclosed |
| EP-0699543-A1 | Printing paper | SONY CORPORATION (JP) | 1996-03-06 | — | — | EP | disclosed |
| CN-1114653-A | Oligomeric hals phophites and hals phosphonites as stabilisers | CIBA GEIGY AG (CH) | 1996-01-10 | — | — | CN | disclosed |
| US-4833023-A | CONTAINING SOILD PLASTICIZER | MITSUBISHI PAPER MILLS, LTD. (JP) | 1989-05-23 | — | — | US | disclosed |
| US-4745026-A | FINE PARTICLE SOLID PLASTICIZER | MITSUBISHI PAPER MILLS, LTD. (JP) | 1988-05-17 | — | — | US | disclosed |
| US-4205076-A | Lipogenesis inhibition by certain esters of substituted benzodioxincarboxylic acids | SHELL OIL COMPANY (US) | 1980-05-27 | — | — | US | disclosed |
| US-4035423-A | Process for the preparation of 3,4-dialkoxyanilines | CIBA-GEIGY CORPORATION (US) | 1977-07-12 | — | — | US | disclosed |