Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR7 | P34969 | 2/20 | 0.35 |
| ▸ | PPARD | Q03181 | 4/20 | 0.35 |
| ▸ | CTSA | P10619 | 2/20 | 0.35 |
| ▸ | VDR | P11473 | 3/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
| ▸ | THRA | P10827 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | RXRA | P19793 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.34 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17804512 | 0.85 | HTR7 (0.38) | HTR7THRBADORA2AADORA1FFAR1 | |
| SCHEMBL22590893 | 0.79 | ADORA2A (0.35) | PPARDCTSAVDRESR1THRA | |
| SCHEMBL21317993 | 0.75 | PARP15 (0.41) | FFAR1ALDH1A1MAPTNPC1RAB9A | |
| SCHEMBL22038754 | 0.75 | FFAR1 (0.41) | PPARDFFAR1 | |
| SCHEMBL20195399 | 0.75 | FFAR1 (0.37) | FFAR1ALDH1A1LMNA | |
| SCHEMBL22038686 | 0.74 | GYS1 (0.39) | PPARDFFAR1ALDH1A1LMNA | |
| SCHEMBL18831565 | 0.74 | SLC22A12 (0.39) | PPARAFFAR1MAPTRAB9A | |
| SCHEMBL22038204 | 0.74 | PARP15 (0.39) | FFAR1ALDH1A1MAPTHPGD | |
| SCHEMBL18831730 | 0.73 | PTPN1 (0.34) | FFAR1ALDH1A1TP53TSHR | |
| SCHEMBL20195482 | 0.73 | CYP3A4 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |