Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NTSR1 | P30989 | 3/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.32 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.31 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.31 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.31 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
| ▸ | GRM5 | P41594 | 2/20 | 0.30 |
| ▸ | HTR2C | P28335 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20686640 | 0.83 | NOTUM (0.35) | NTSR1 | |
| SCHEMBL18871241 | 0.81 | PDK2 (0.33) | PDK2PDK4HTR1A | |
| SCHEMBL20342696 | 0.79 | NOTUM (0.34) | ADRA1APDK2PDK4CYP1A2CYP2D6 | |
| SCHEMBL18185030 | 0.78 | ADRA1A (0.35) | ADRA1APDK2PDK4CYP2D6CYP2C19 | |
| SCHEMBL20686851 | 0.77 | MRGPRX4 (0.39) | HTR1ATSHRLMNA | |
| SCHEMBL22038794 | 0.77 | HTR7 (0.44) | ADRA1ACYP1A2HTR1AADRA2ACYP2D6 | |
| SCHEMBL20195514 | 0.76 | HTR1A (0.39) | ADRA1ACYP1A2HTR1AADRA2ACYP2D6 | |
| SCHEMBL19909901 | 0.76 | AOC3 (0.31) | CYP1A2CYP2D6TSHRHTR1DLMNA | |
| SCHEMBL20686707 | 0.75 | MRGPRX4 (0.41) | CYP1A2HTR1ACYP2C19 | |
| SCHEMBL18871267 | 0.75 | SLC22A12 (0.33) | ADRA1ACYP1A2HTR1AADRA2ACYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2990404-B1 | TETRAZOLINONE COMPOUND AND USE OF SAME | SUMITOMO CHEMICAL CO (JP) | 2020-05-27 | — | — | EP | disclosed |
| EP-3029030-B1 | TETRAZOLINONE COMPOUND, AND USE THEREFOR | SUMITOMO CHEMICAL CO (JP) | 2019-09-04 | — | — | EP | disclosed |
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |