SCHEMBL20195413

SCHEMBL20195413

CN(N)C(=O)N(N)c1cccc(C(F)F)c1COc1cccc(Br)n1

nearest known ligand 0.39

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR7 P34969 1/20 0.39
NR1H4 Q96RI1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22037708 0.85 HTR7 (0.42) HTR7NR1H4
SCHEMBL20195562 0.84 GLP1R (0.36) NR1H4
SCHEMBL22038784 0.84 HTR7 (0.41) HTR7NR1H4
SCHEMBL22037272 0.84 HTR7 (0.41) HTR7
SCHEMBL22038791 0.83 HTR7 (0.41) HTR7
SCHEMBL18831574 0.79 PDCD1 (0.32)
SCHEMBL20195455 0.78 NPC1 (0.38)
SCHEMBL20195615 0.76 GUCY1B2 (0.31)
SCHEMBL20686655 0.76 MRGPRX4 (0.37)
SCHEMBL18831773 0.76 MRGPRX4 (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3029035-B1 TETRAZOLINONE COMPOUND, AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2018-05-30 EP disclosed