Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GRM5 | P41594 | 1/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 4/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.32 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195402 | 0.85 | GABRA5 (0.39) | NPC1RAB9ASMN1; SMN2GRM5GABRA5 | |
| SCHEMBL20195398 | 0.85 | RXFP1 (0.36) | NPC1RAB9AGRM5GABRA5ALDH1A1 | |
| SCHEMBL20195459 | 0.84 | ADORA2A (0.38) | NPC1RAB9ASMN1; SMN2GRM5GABRA5 | |
| SCHEMBL20195413 | 0.78 | HTR7 (0.39) | — | |
| SCHEMBL20195562 | 0.73 | GLP1R (0.36) | — | |
| SCHEMBL22037708 | 0.72 | HTR7 (0.42) | CYP2D6CYP2C19 | |
| SCHEMBL22038784 | 0.72 | HTR7 (0.41) | SMN1; SMN2 | |
| SCHEMBL22037272 | 0.72 | HTR7 (0.41) | — | |
| SCHEMBL20195412 | 0.72 | NR1H4 (0.32) | — | |
| SCHEMBL22037199 | 0.71 | GABRA5 (0.33) | GABRA5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |