SCHEMBL20195615

SCHEMBL20195615

Cc1ncncc1OCc1c(C(F)F)cccc1N(N)C(=O)N(C)N

nearest known ligand 0.31

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
GUCY1B2 O75343 2/20 0.31
GUCY1A2 P33402 2/20 0.31
GUCY1A1 Q02108 2/20 0.31
GUCY1B1 Q02153 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20195528 0.87 L3MBTL1 (0.30) GUCY1B2GUCY1A2GUCY1A1GUCY1B1
SCHEMBL20195538 0.85 MEN1 (0.30)
SCHEMBL18831773 0.80 MRGPRX4 (0.34)
SCHEMBL18831778 0.79 SLC22A12 (0.33)
SCHEMBL20686655 0.78 MRGPRX4 (0.37)
SCHEMBL18831574 0.77 PDCD1 (0.32)
SCHEMBL20195413 0.76 HTR7 (0.39)
SCHEMBL20686665 0.76 PTGDR2 (0.40)
SCHEMBL20195603 0.74
SCHEMBL20195562 0.73 GLP1R (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3029035-B1 TETRAZOLINONE COMPOUND, AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2018-05-30 EP disclosed