SCHEMBL20195427

SCHEMBL20195427

Cc1ccc(-c2cc(C)c(OCc3c(C)cccc3N(N)C(=O)NN)nc2C)cc1

nearest known ligand 0.33

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 2/20 0.33
CNR2 P34972 2/20 0.33
CTSA P10619 1/20 0.33
CD38 P28907 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.31
FFAR1 O14842 1/20 0.31
HTT P42858 1/20 0.31
KMT2A Q03164 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
CHRNA7 P36544 1/20 0.31
ABHD6 Q9BV23 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22038663 0.79 FFAR4 (0.42) FFAR1
SCHEMBL20195489 0.79 CD38 (0.32) CD38KMT2A
SCHEMBL20195467 0.78 FFAR1 (0.42) CTSAFFAR1CHRNA7
SCHEMBL22059937 0.77 MRGPRX4 (0.46) SMN1; SMN2KMT2AL3MBTL1
SCHEMBL20195430 0.77 PSMB5 (0.36) FFAR1KMT2ANPSR1L3MBTL1
SCHEMBL23506204 0.74 NPC1 (0.37) CD38KMT2A
SCHEMBL20195508 0.73 FFAR1 (0.36) CD38SMN1; SMN2FFAR1
SCHEMBL20902011 0.73 MEN1 (0.38) CD38SMN1; SMN2KMT2AL3MBTL1
SCHEMBL22038156 0.73 NPC1 (0.39) SMN1; SMN2FFAR1KMT2A
SCHEMBL22038781 0.73 P2RX7 (0.36) CD38SMN1; SMN2FFAR1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3029035-B1 TETRAZOLINONE COMPOUND, AND USE THEREOF SUMITOMO CHEMICAL CO (JP) 2018-05-30 EP disclosed