Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PSMB5 | P28074 | 4/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | SQOR | Q9Y6N5 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195485 | 0.82 | CYP3A4 (0.35) | CYP1A2CYP2C9CYP2C19CYP3A4CYP2D6 | |
| SCHEMBL22038661 | 0.78 | FFAR1 (0.41) | FFAR1SLC22A12CD274 | |
| SCHEMBL20195461 | 0.77 | CYP1A2 (0.33) | SLC22A12CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL20195427 | 0.77 | CNR1 (0.33) | L3MBTL1FFAR1KMT2ANPSR1 | |
| SCHEMBL22037215 | 0.75 | HTR7 (0.45) | FFAR1MEN1KMT2ASLC22A12KDM4E | |
| SCHEMBL22038664 | 0.74 | GABRA5 (0.39) | FFAR1SLC22A12KDM4EGAA | |
| SCHEMBL22037248 | 0.74 | CD274 (0.42) | FFAR1CD274 | |
| SCHEMBL22037235 | 0.74 | AURKA (0.38) | L3MBTL1MEN1KMT2AKDM4ECYP1A2 | |
| SCHEMBL20195388 | 0.73 | HTR7 (0.35) | FFAR1HPGDESR2 | |
| SCHEMBL20686651 | 0.72 | NISCH (0.42) | L3MBTL1SLC22A12KDM4ECYP1A2CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |