Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.33 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CBFB | Q13951 | 1/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | GRM5 | P41594 | 2/20 | 0.32 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | JAK2 | O60674 | 1/20 | 0.30 |
| ▸ | JAK1 | P23458 | 1/20 | 0.30 |
| ▸ | TYK2 | P29597 | 1/20 | 0.30 |
| ▸ | JAK3 | P52333 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195429 | 0.85 | MGAT2 (0.33) | GABRA5 | |
| SCHEMBL17796912 | 0.84 | GRM5 (0.38) | FLT3GSK3BCBFBGRM5GABRA5 | |
| SCHEMBL20195457 | 0.83 | CA12 (0.34) | GABRA5 | |
| SCHEMBL17614621 | 0.82 | GABRA5 (0.36) | GABRA5JAK1TYK2JAK3 | |
| SCHEMBL16437463 | 0.81 | GRM5 (0.35) | FLT3GSK3BCBFBGRM5GABRA5 | |
| SCHEMBL20195527 | 0.80 | HCAR2 (0.33) | DHFRGABRA5CYP3A4CYP2D6SMN1; SMN2 | |
| SCHEMBL17788432 | 0.79 | PRMT5 (0.35) | FLT3GSK3BCBFBCYP3A4CYP2D6 | |
| SCHEMBL22038152 | 0.77 | BTK (0.32) | — | |
| SCHEMBL22037221 | 0.76 | BTK (0.38) | LMNAHTTSMN1; SMN2 | |
| SCHEMBL22038749 | 0.76 | BTK (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |