Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 2/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.32 |
| ▸ | MGAM | O43451 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | SI | P14410 | 1/20 | 0.32 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | PPARD | Q03181 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CNR1 | P21554 | 1/20 | 0.31 |
| ▸ | TACR3 | P29371 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17614621 | 0.91 | GABRA5 (0.36) | BTKGAAKDM4ENPC1ALDH1A1 | |
| SCHEMBL22038749 | 0.89 | BTK (0.33) | BTK | |
| SCHEMBL22037221 | 0.89 | BTK (0.38) | BTKGAAKDM4ENPC1ALDH1A1 | |
| SCHEMBL22038123 | 0.86 | SCN5A (0.40) | GAAKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL17547316 | 0.84 | CNR1 (0.34) | CNR1 | |
| SCHEMBL16206004 | 0.83 | HTR7 (0.33) | TNKSTNKS2PARP2MGAMGAA | |
| SCHEMBL22038161 | 0.83 | ALDH1A1 (0.39) | GAAKDM4ENPC1ALDH1A1RAB9A | |
| SCHEMBL15352336 | 0.81 | SIGMAR1 (0.37) | GAANPC1ALDH1A1PKMRAB9A | |
| SCHEMBL17547303 | 0.81 | SMN1; SMN2 (0.35) | GAANPC1ALDH1A1RAB9AMAPT | |
| SCHEMBL17547212 | 0.79 | PDE10A (0.34) | BTKKDM4EALDH1A1RAB9ATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2990404-B1 | TETRAZOLINONE COMPOUND AND USE OF SAME | SUMITOMO CHEMICAL CO (JP) | 2020-05-27 | — | — | EP | disclosed |