Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MGAT2 | Q10469 | 2/20 | 0.33 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
| ▸ | BRD7 | Q9NPI1 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.31 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195436 | 0.85 | FLT3 (0.33) | GABRA5 | |
| SCHEMBL20195527 | 0.85 | HCAR2 (0.33) | GABRG2GABRB3GABRA5 | |
| SCHEMBL17804259 | 0.83 | BRD9 (0.33) | BRD9BRD7GABRG2GABRB3GABRA5 | |
| SCHEMBL20195449 | 0.83 | ALDH1A1 (0.36) | MGAT2MOGAT2BRD9BRD7PDE10A | |
| SCHEMBL20195457 | 0.81 | CA12 (0.34) | GABRA5 | |
| SCHEMBL17811664 | 0.80 | — | — | |
| SCHEMBL17614621 | 0.79 | GABRA5 (0.36) | GABRA5KCNH2PDE10A | |
| SCHEMBL22038662 | 0.79 | SLC22A12 (0.45) | MGAT2MOGAT2FFAR1 | |
| SCHEMBL22038152 | 0.79 | BTK (0.32) | — | |
| SCHEMBL22037221 | 0.77 | BTK (0.38) | MGAT2MOGAT2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |