Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | MGAT2 | Q10469 | 2/20 | 0.32 |
| ▸ | MOGAT2 | Q3SYC2 | 2/20 | 0.32 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | HTR7 | P34969 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17547212 | 0.86 | PDE10A (0.34) | ALDH1A1RAB9AKDM4ETP53HPGD | |
| SCHEMBL17815775 | 0.85 | ADORA3 (0.33) | ALDH1A1RAB9AKDM4ETP53HPGD | |
| SCHEMBL20195429 | 0.83 | MGAT2 (0.33) | MGAT2MOGAT2PDE10ABRD9BRD7 | |
| SCHEMBL17811650 | 0.76 | ADORA3 (0.31) | ADORA3BRD9BRD7 | |
| SCHEMBL17804244 | 0.76 | BRD9 (0.36) | ALDH1A1KDM4EHPGDLMNATSHR | |
| SCHEMBL17796909 | 0.75 | CD274 (0.35) | PDE10ALMNA | |
| SCHEMBL20195527 | 0.74 | HCAR2 (0.33) | ALDH1A1HPGDHSD17B10MEN1KMT2A | |
| SCHEMBL20195436 | 0.74 | FLT3 (0.33) | LMNAHTT | |
| SCHEMBL22563886 | 0.73 | — | — | |
| SCHEMBL18504518 | 0.73 | HSP90AA1 (0.31) | HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |