Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | DRD1 | P21728 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | TRPV4 | Q9HBA0 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.32 |
| ▸ | RXRA | P19793 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195625 | 0.77 | NPC1 (0.38) | SGMS2HTTL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL20195662 | 0.75 | P2RX7 (0.40) | SGMS2HTTKMT2AALDH1A1MAPT | |
| SCHEMBL20195555 | 0.73 | HTR2C (0.39) | SGMS2ALDH1A1MAPTKDM4EP2RX7 | |
| SCHEMBL23506201 | 0.72 | SCN9A (0.36) | SGMS2ALDH1A1MAPTKDM4E | |
| SCHEMBL23506123 | 0.72 | SYK (0.36) | SGMS2HTTL3MBTL1KMT2AALDH1A1 | |
| SCHEMBL20844961 | 0.72 | P2RX7 (0.32) | ALDH1A1MAPTKDM4EP2RX7 | |
| SCHEMBL20195533 | 0.71 | P2RX7 (0.38) | SGMS2L3MBTL1KMT2AALDH1A1MAPT | |
| SCHEMBL22059937 | 0.71 | MRGPRX4 (0.46) | L3MBTL1KMT2AALDH1A1MAPTLMNA | |
| SCHEMBL22563824 | 0.71 | SMN1; SMN2 (0.37) | HTTL3MBTL1KMT2AALDH1A1MAPT | |
| SCHEMBL20195467 | 0.71 | FFAR1 (0.42) | SGMS2ALDH1A1MAPTKDM4EGRIN2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |