Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | SGMS2 | Q8NHU3 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195504 | 0.86 | GRM5 (0.36) | NPC1HTTADORA2AADORA1KMT2A | |
| SCHEMBL20195598 | 0.79 | KMT2A (0.49) | NPC1HTTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL20195451 | 0.78 | ALDH1A1 (0.45) | NPC1HTTADORA2AADORA1KMT2A | |
| SCHEMBL20195552 | 0.78 | ALDH1A1 (0.43) | NPC1HTTKMT2AL3MBTL1ALDH1A1 | |
| SCHEMBL20195470 | 0.77 | SGMS2 (0.33) | HTTKMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL20195662 | 0.76 | P2RX7 (0.40) | NPC1HTTADORA2AADORA1KMT2A | |
| SCHEMBL20195434 | 0.74 | ALDH1A1 (0.50) | NPC1KMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL20195505 | 0.73 | ADRA2A (0.33) | HTTKMT2AL3MBTL1ALDH1A1LMNA | |
| SCHEMBL20195500 | 0.73 | HTT (0.33) | HTTKMT2AL3MBTL1LMNASGMS2 | |
| SCHEMBL20195398 | 0.72 | RXFP1 (0.36) | NPC1HTTADORA2AADORA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |