Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 2/20 | 0.43 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.43 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20195435 | 0.82 | ALDH1A1 (0.45) | GABRA5ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL20195519 | 0.81 | LMNA (0.46) | GABRA5ALDH1A1KMT2ALMNAMAPT | |
| SCHEMBL20195559 | 0.78 | ALDH1A1 (0.43) | ALDH1A1KMT2AMAPTMEN1SMN1; SMN2 | |
| SCHEMBL18504900 | 0.77 | KMT2A (0.33) | ALDH1A1KMT2AMAPTNR1H4SMN1; SMN2 | |
| SCHEMBL22563924 | 0.77 | NR1H4 (0.33) | ALDH1A1KMT2ANR1H4 | |
| SCHEMBL17191142 | 0.72 | ALDH1A1 (0.38) | ALDH1A1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL19229479 | 0.71 | ALDH1A1 (0.43) | ALDH1A1KMT2AMAPTMEN1TDP1 | |
| SCHEMBL17146181 | 0.69 | ALDH1A1 (0.41) | ALDH1A1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL17191144 | 0.69 | ALDH1A1 (0.36) | ALDH1A1KMT2ALMNAMAPTMEN1 | |
| SCHEMBL15352610 | 0.68 | TDP1 (0.64) | ALDH1A1KMT2ALMNAMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3029035-B1 | TETRAZOLINONE COMPOUND, AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2018-05-30 | — | — | EP | disclosed |