Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.44 |
| ▸ | GAA | P10253 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | HTR1E | P28566 | 1/20 | 0.38 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL778610 | 0.89 | SMN1; SMN2 (0.52) | HPGDSMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL13321940 | 0.87 | GAA (0.53) | SMN1; SMN2GAACYP2C19TSHRKCNA5 | |
| SCHEMBL28318624 | 0.83 | SMN1; SMN2 (0.53) | SMN1; SMN2GAACYP2C19LMNATSHR | |
| SCHEMBL10426380 | 0.79 | SMN1; SMN2 (0.52) | SMN1; SMN2GAALMNATSHRMEN1 | |
| SCHEMBL18486590 | 0.78 | HPGD (0.45) | HPGDSMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL24817133 | 0.76 | SMN1; SMN2 (0.42) | HPGDSMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL778811 | 0.76 | SMN1; SMN2 (0.42) | HPGDSMN1; SMN2GAANPC1RAB9A | |
| SCHEMBL7930260 | 0.76 | SMN1; SMN2 (0.44) | SMN1; SMN2GAAKCNA5 | |
| SCHEMBL64426 | 0.74 | GAA (0.38) | SMN1; SMN2GAANPC1RAB9AMEN1 | |
| SCHEMBL9927225 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2GAACYP2C19LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327024-B1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | LG CHEMICAL LTD (KR) | 2019-07-17 | — | — | EP | disclosed |
| EP-3327024-A1 | HETEROCYCLIC COMPOUND AND ORGANIC LIGHT EMITTING DIODE COMPRISING SAME | LG Chem, Ltd. (KR) | 2018-05-30 | — | — | EP | disclosed |