SCHEMBL64426

SCHEMBL64426

Nc1ccc(P(=O)(c2ccc(N)cc2)C2CCCCC2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 3/20 0.38
EPHX1 P07099 2/20 0.38
RAB9A P51151 2/20 0.38
NFE2L2 Q16236 1/20 0.36
CYP19A1 P11511 5/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
TBXAS1 P24557 1/20 0.33
ALDH1A1 P00352 3/20 0.32
L3MBTL1 Q9Y468 2/20 0.32
DPEP1 P16444 1/20 0.32
MEN1 O00255 2/20 0.32
MAPT P10636 2/20 0.32
KMT2A Q03164 2/20 0.32
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
USP2 O75604 1/20 0.31
TP53 P04637 1/20 0.31
POLB P06746 1/20 0.31
THRB P10828 1/20 0.31
ALOX15 P16050 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL778610 0.79 SMN1; SMN2 (0.52) GAARAB9ASMN1; SMN2ALDH1A1L3MBTL1
SCHEMBL13321940 0.77 GAA (0.53) GAASMN1; SMN2ALDH1A1L3MBTL1MAPT
SCHEMBL20195697 0.74 HPGD (0.44) GAAEPHX1RAB9ASMN1; SMN2ALDH1A1
SCHEMBL28318624 0.72 SMN1; SMN2 (0.53) GAASMN1; SMN2ALDH1A1L3MBTL1MEN1
Biphenyl SCHEMBL11225889 0.68 ALDH1A1 (0.47) GAAEPHX1RAB9ANFE2L2CYP19A1
SCHEMBL28273107 0.68 ALDH1A1 (0.47) GAAEPHX1RAB9ANFE2L2CYP19A1
SCHEMBL7930260 0.67 SMN1; SMN2 (0.44) GAASMN1; SMN2
SCHEMBL10426380 0.67 SMN1; SMN2 (0.52) GAASMN1; SMN2ALDH1A1L3MBTL1MEN1
SCHEMBL24817134 0.66 CYP3A4 (0.35) GAARAB9ASMN1; SMN2ALDH1A1MEN1
SCHEMBL3289719 0.65 CYP3A4 (0.50) ALDH1A1MEN1MAPTKMT2AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0330456-B1 Preparation of silicon-containing polyimide precursor and cured polyimides obtained therefrom CHISSO CORP (JP) 1994-09-07 EP claimed
CN-109937380-B Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element 日产化学株式会社 2022-04-19 CN disclosed
CN-109937380-A Aligning agent for liquid crystal, liquid crystal orientation film and liquid crystal indicate element 日产化学株式会社 2019-06-25 CN disclosed
CN-103797408-B Liquid crystal aligning agent, liquid crystal alignment film and liquid crystal display element 日产化学工业株式会社 2019-02-19 CN disclosed
EP-2158253-B1 METHOD OF PURIFYING A POLYMER SABIC GLOBAL TECHNOLOGIES BV (NL) 2017-04-05 EP disclosed
US-9459494-B2 Liquid crystal aligning agent and liquid crystal display device employing it NISSAN CHEMICAL INDUSTRIES, LTD. (JP) 2016-10-04 US disclosed
EP-2191059-B1 COATED FIBER AND METHOD FOR MAKING THE COATED FIBER SABIC INNOVATIVE PLASTICS IP (NL) 2015-04-01 EP disclosed
US-20140023798-A1 LIQUID CRYSTAL ALIGNING AGENT AND LIQUID CRYSTAL DISPLAY DEVICE EMPLOYING IT NISSAN CHEMICAL INDUSTRIES LIMITED (JP) 2014-01-23 US disclosed
US-20140017398-A1 MANUFACTURING METHOD OF LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL ALIGNMENT ELEMENT CHI MEI CORPORATION (TW) 2014-01-16 US disclosed
US-20130310572-A1 LIQUID CRYSTAL ALIGNMENT FILM AND LIQUID CRYSTAL ALIGNMENT ELEMENT USING THE SAME CHI MEI CORPORATION (TW) 2013-11-21 US disclosed
EP-0410702-A2 Printing ink composition Chisso Corporation (JP) 1991-01-30 EP disclosed
US-4963635-A REACTING A FLUORINE-CONTAINING DIANHYDRIDE OR DIANHYDRIDE, A FLUORINE-CONTAINING DIAMINE OR A DEIAMINE AND AN AMINO-CONTAINING OXYSILANE COMPOUND CHISSO CORPORATION (JP) 1990-10-16 US disclosed
US-4963649-A LOW GLASS TRANSITION TEMPERATURES; FOR HOT MELT ADHESIVES, PREPREGS ETHYL CORPORATION (US) 1990-10-16 US disclosed
EP-0341028-A2 Process for the preparation of photosensitive polymers Chisso Corporation (JP) 1989-11-08 EP disclosed
EP-0330456-A1 Preparation of silicon-containing polyimide precursor and cured polyimides obtained therefrom CHISSO CORPORATION (JP) 1989-08-30 EP disclosed
US-4687836-A FROM 3,3*-DIAMINOBENZOPHENONE AND BENZOPHENONETETRACARBOXYLIC ACID MITSUI TOATSU CHEMICALS, INC. (JP) 1987-08-18 US disclosed
EP-0179604-A2 Polyimide adhesives, coats and prepreg MITSUI TOATSU CHEMICALS, Inc. (JP) 1986-04-30 EP disclosed
US-4124651-A Process for the production of polyamide-polyamide-acid copolymers CIBA-GEIGY CORPORATION (US) 1978-11-07 US disclosed
US-3950308-A POLYAMIDES, POLYIMIDES, POLYAMIDE-IMIDES CIBA-GEIGY CORPORATION (US) 1976-04-13 US disclosed
US-3948835-A POLYAMIDE, POLYAMIDE-ACID OR POLYAMIDE-AMIDE-ACIDS CIBA-GEIGY CORPORATION (US) 1976-04-06 US disclosed