Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PAOX | Q6QHF9 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20196325 | 0.98 | PAOX (0.40) | PAOX | |
| SCHEMBL22883181 | 0.87 | ALDH1A1 (0.33) | PAOXALDH1A1 | |
| SCHEMBL13459034 | 0.82 | ADH1C (0.37) | — | |
| SCHEMBL23074300 | 0.81 | EPHX2 (0.30) | — | |
| SCHEMBL25558351 | 0.81 | MEN1 (0.31) | — | |
| SCHEMBL24380606 | 0.81 | ADH1C (0.40) | — | |
| SCHEMBL13973878 | 0.80 | CA12 (0.35) | — | |
| SCHEMBL18932352 | 0.79 | FAAH (0.47) | — | |
| SCHEMBL17011648 | 0.78 | PAOX (0.46) | PAOXACHEALDH1A1 | |
| SCHEMBL22992436 | 0.77 | KDM7A (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3327027-A1 | CYTOTOXIC PEPTIDES AND ANTIBODY DRUG CONJUGATES THEREOF | Pfizer Inc (US) | 2018-05-30 | — | — | EP | disclosed |