Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 3/20 | 0.40 |
| ▸ | G6PC1 | P35575 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | HSD17B3 | P37058 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.36 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.36 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16838881 | 0.94 | HSD17B3 (0.39) | OPRM1L3MBTL1HSD17B3FFAR4 | |
| SCHEMBL7458158 | 0.84 | OPRM1 (0.46) | OPRM1TAAR1OPRK1OPRD1 | |
| SCHEMBL7455241 | 0.83 | TAAR1 (0.46) | OPRM1L3MBTL1TAAR1EPHX2OPRK1 | |
| SCHEMBL873249 | 0.83 | TAAR1 (0.46) | OPRM1L3MBTL1TAAR1EPHX2OPRK1 | |
| SCHEMBL987019 | 0.79 | OPRM1 (0.48) | OPRM1EPHX2 | |
| SCHEMBL16838885 | 0.79 | OPRM1 (0.48) | OPRM1EPHX2 | |
| Ether SCHEMBL2017378 | 0.78 | L3MBTL1 (0.47) | OPRM1L3MBTL1TAAR1HSD17B3OPRK1 | |
| SCHEMBL6527498 | 0.75 | MEN1 (0.39) | OPRM1 | |
| SCHEMBL21535464 | 0.75 | OPRM1 (0.59) | OPRM1OPRK1OPRD1 | |
| SCHEMBL5009548 | 0.73 | CA1 (0.41) | OPRM1TAAR1HSD17B3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2881384-B1 | PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2018-05-30 | — | — | EP | disclosed |