Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.48 |
| ▸ | OPRL1 | P41146 | 2/20 | 0.48 |
| ▸ | DPP4 | P27487 | 1/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | CARM1 | Q86X55 | 2/20 | 0.46 |
| ▸ | PRMT6 | Q96LA8 | 2/20 | 0.46 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.46 |
| ▸ | PRMT8 | Q9NR22 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 1/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.45 |
| ▸ | CTSK | P43235 | 1/20 | 0.45 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | BCHE | P06276 | 1/20 | 0.41 |
| ▸ | PSEN1 | P49768 | 2/20 | 0.39 |
| ▸ | PSEN2 | P49810 | 2/20 | 0.39 |
| ▸ | APH1B | Q8WW43 | 2/20 | 0.39 |
| ▸ | NCSTN | Q92542 | 2/20 | 0.39 |
| ▸ | APH1A | Q96BI3 | 2/20 | 0.39 |
| ▸ | PSENEN | Q9NZ42 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16838885 | 1.00 | OPRM1 (0.48) | OPRM1OPRL1DPP4SIGMAR1CARM1 | |
| SCHEMBL11998001 | 0.90 | CTSL (0.43) | OPRM1OPRL1DPP4SIGMAR1CARM1 | |
| SCHEMBL6469380 | 0.85 | OPRM1 (0.59) | OPRM1OPRL1DPP4SIGMAR1CARM1 | |
| SCHEMBL24899061 | 0.84 | CTSL (0.46) | OPRM1OPRL1DPP4SIGMAR1CARM1 | |
| SCHEMBL21141929 | 0.84 | CTSL (0.46) | OPRM1OPRL1DPP4SIGMAR1CARM1 | |
| SCHEMBL16761764 | 0.83 | CARM1 (0.48) | CARM1PRMT6BCHE | |
| SCHEMBL16762086 | 0.83 | CARM1 (0.48) | CARM1PRMT6BCHE | |
| SCHEMBL16838881 | 0.83 | HSD17B3 (0.39) | OPRM1SIGMAR1HRH3HTR2AHTR2C | |
| SCHEMBL16761765 | 0.83 | CARM1 (0.48) | CARM1PRMT6BCHE | |
| SCHEMBL16761694 | 0.83 | CARM1 (0.48) | CARM1PRMT6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025122832-A1 | IMIDAZOLE COMPOUNDS AND THEIR USE AS SODIUM CHANNEL INHIBITORS | GENEP INC. (US) | 2025-06-12 | — | — | WO | disclosed |
| US-20250066349-A1 | CYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2025-02-27 | — | — | US | disclosed |
| WO-2025037229-A1 | COMPOUNDS AND COMPOSITIONS FOR MODULATING THE ACTIVITY OF ERK | NOVARTIS AG (CH) | 2025-02-20 | — | — | WO | disclosed |
| EP-4444420-A2 | CYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | Prothena Biosciences Limited (IE) | 2024-10-16 | — | — | EP | disclosed |
| CN-116802182-A | Pyrazolopyridine derivatives and uses thereof | 诺华股份有限公司 | 2023-09-22 | — | — | CN | disclosed |
| WO-2023107723-A2 | METHODS FOR TREATING NEUROLOGICAL DISORDERS | PROTHENA BIOSCIENCES LIMITED (IE) | 2023-06-15 | — | — | WO | disclosed |
| CN-110997871-A | Liquid crystal compounds | 默克专利股份有限公司 | 2020-04-10 | — | — | CN | disclosed |
| WO-2019034588-A1 | LIQUID-CRYSTALLINE COMPOUNDS | MERCK PATENT GMBH (DE) | 2019-02-21 | — | — | WO | disclosed |
| WO-2019034588-A1 | LIQUID-CRYSTALLINE COMPOUNDS | MERCK PATENT GMBH (DE) | 2019-02-21 | — | — | WO | disclosed |
| US-9550793-B2 | Spirocyclic compounds, compositions and medicinal applications thereof | ADVINUS THERAPEUTICS LIMITED (IN) | 2017-01-24 | — | — | US | disclosed |
| US-20150218187-A1 | SPIROCYCLIC COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF | IMPETIS BIOSCIENCES LTD. (IN) | 2015-08-06 | — | — | US | disclosed |
| US-8791303-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-07-29 | — | — | US | disclosed |
| US-8791303-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-07-29 | — | — | US | disclosed |
| US-8791303-B2 | Herbicides | SYNGENTA LIMITED (GB) | 2014-07-29 | — | — | US | disclosed |
| US-20120178623-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-07-12 | — | — | US | disclosed |
| US-20120178623-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-07-12 | — | — | US | disclosed |
| US-20120178623-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-07-12 | — | — | US | disclosed |
| EP-2454223-A1 | HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE DERIVATIVES | Syngenta Limited (GB) | 2012-05-23 | — | — | EP | disclosed |
| WO-2011007146-A1 | HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE DERIVATIVES | SYNGENTA LIMITED (GB) | 2011-01-20 | — | — | WO | disclosed |
| WO-2011007146-A1 | HERBICIDALLY ACTIVE 2-(SUBSTITUTED-PHENYL)-CYCLOPENTANE-1,3-DIONE DERIVATIVES | SYNGENTA LIMITED (GB) | 2011-01-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150218187-A1 | SPIROCYCLIC COMPOUNDS, COMPOSITIONS AND MEDICINAL APPLICATIONS THEREOF | DGAT1, DGAT2, CPT1A | OPRM1 2065/4885OPRL1 1971/4885DPP4 1463/4885 |
| US-20120178623-A1 | NOVEL HERBICIDES | DDT, CBR3, C9 | OPRM1 872/4885OPRL1 1215/4885DPP4 1526/4885 |
| US-20250066349-A1 | CYCLIC COMPOUNDS AND THEIR USE FOR THE TREATMENT OF NEUROLOGICAL DISORDERS | DYRK2, DYRK1A, PYGB | OPRM1 1812/4885OPRL1 1416/4885DPP4 4574/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.