Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 9/20 | 0.57 |
| ▸ | MAOB | P27338 | 2/20 | 0.55 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | PPARA | Q07869 | 1/20 | 0.50 |
| ▸ | LTA4H | P09960 | 2/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.46 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8890073 | 0.88 | FFAR1 (0.58) | FFAR1LTA4HFFAR4 | |
| SCHEMBL8888760 | 0.88 | FFAR1 (0.58) | FFAR1LTA4HFFAR4 | |
| SCHEMBL8887581 | 0.88 | FFAR1 (0.58) | FFAR1LTA4HFFAR4 | |
| SCHEMBL8890454 | 0.87 | FFAR1 (0.59) | FFAR1LTA4HFFAR4 | |
| SCHEMBL12329630 | 0.86 | PPARA (0.56) | PPARGPPARAHDAC8CYP4Z1 | |
| SCHEMBL765019 | 0.86 | PPARA (0.56) | PPARGPPARAHDAC8CYP4Z1 | |
| SCHEMBL14325320 | 0.85 | CYP4F2 (0.55) | PPARGPPARAHDAC8CYP4Z1 | |
| SCHEMBL19825762 | 0.83 | FFAR1 (0.61) | FFAR1LTA4HFFAR4 | |
| SCHEMBL765924 | 0.81 | ALOX5 (0.57) | PPARGPPARAHDAC8CYP4Z1 | |
| SCHEMBL12548347 | 0.81 | CYP4Z1 (0.58) | LTA4HCYP4Z1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2881384-B1 | PARTIALLY SATURATED NITROGEN-CONTAINING HETEROCYCLIC COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 2018-05-30 | — | — | EP | disclosed |