SCHEMBL19825762

SCHEMBL19825762

CCOC(=O)CCCc1ccc(OCc2ccccc2)cc1

nearest known ligand 0.61

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 5/20 0.61
FFAR4 Q5NUL3 2/20 0.61
ALOX5 P09917 3/20 0.61
LTA4H P09960 7/20 0.58
EPHX2 P34913 1/20 0.58
NR1H4 Q96RI1 1/20 0.57
LMNA P02545 1/20 0.56
L3MBTL1 Q9Y468 1/20 0.56
LTB4R Q15722 1/20 0.54
LTB4R2 Q9NPC1 1/20 0.54
ALDH1A1 P00352 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8890454 0.96 FFAR1 (0.59) FFAR1FFAR4ALOX5LTA4HEPHX2
SCHEMBL8888760 0.95 FFAR1 (0.58) FFAR1FFAR4ALOX5LTA4HEPHX2
SCHEMBL8890073 0.95 FFAR1 (0.58) FFAR1FFAR4ALOX5LTA4HEPHX2
SCHEMBL8887581 0.95 FFAR1 (0.58) FFAR1FFAR4ALOX5LTA4HEPHX2
SCHEMBL3091164 0.92 FFAR1 (0.68) FFAR1FFAR4ALOX5LTA4HNR1H4
SCHEMBL7907176 0.90 FFAR1 (0.66) FFAR1FFAR4ALOX5LTA4HEPHX2
SCHEMBL6338423 0.89 LTA4H (0.64) LTA4HNR1H4LMNAL3MBTL1ALDH1A1
SCHEMBL1115103 0.88 LTA4H (0.65) LTA4HNR1H4LMNAL3MBTL1ALDH1A1
SCHEMBL2773462 0.87 FFAR1 (0.68) FFAR1FFAR4ALOX5NR1H4LMNA
SCHEMBL12064833 0.87 ALOX5 (0.72) ALOX5LTA4H

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11773077-B2 Compounds containing carbon-carbon linker as GPR120 agonists Piramal Enterprises Limited (IN) 2023-10-03 US disclosed
US-10941133-B2 Compounds containing carbon-carbon linker as GPR120 agonists Piramal Enterprises Limited (IN) 2021-03-09 US disclosed
US-20210053938-A1 COMPOUNDS CONTAINING CARBON-CARBON LINKER AS GPR120 AGONISTS Piramal Enterprises Limited (IN) 2021-02-25 US disclosed
US-20180030031-A1 COMPOUNDS CONTAINING CARBON-CARBON LINKER AS GPR120 AGONISTS Piramal Enterprises Limited (IN) 2018-02-01 US disclosed
CN-1349990-A Heterocyclic compound, its preparation and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2002-05-22 CN disclosed
CN-1077107-C Heterocyclic compounds, their preparation and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2002-01-02 CN disclosed
CN-1223653-A Heterocyclic compounds, their preparation and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1999-07-21 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11773077-B2 Compounds containing carbon-carbon linker as GPR120 agonists GPR180, GPR68, GPR88 FFAR1 20/4885FFAR4 42/4885ALOX5 1326/4885
US-20180030031-A1 COMPOUNDS CONTAINING CARBON-CARBON LINKER AS GPR120 AGONISTS GPR180, GPR68, GPR88 FFAR1 20/4885FFAR4 42/4885ALOX5 1326/4885
US-10941133-B2 Compounds containing carbon-carbon linker as GPR120 agonists GPR180, GPR68, GPR88 FFAR1 20/4885FFAR4 42/4885ALOX5 1326/4885
US-20210053938-A1 COMPOUNDS CONTAINING CARBON-CARBON LINKER AS GPR120 AGONISTS GPR180, GPR68, GPR88 FFAR1 20/4885FFAR4 42/4885ALOX5 1326/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.