Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.37 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.32 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2021495 | 0.84 | ZAP70 (0.40) | GRIA1 | |
| SCHEMBL2026164 | 0.81 | LMNA (0.36) | ADORA3GRIA1 | |
| SCHEMBL2024478 | 0.77 | GRIA1 (0.31) | GRIA1 | |
| SCHEMBL12638151 | 0.75 | ADORA3 (0.39) | ADORA3HCAR3 | |
| SCHEMBL2022563 | 0.75 | HPGD (0.35) | GRIA1 | |
| SCHEMBL2020707 | 0.72 | ADORA3 (0.43) | ADORA3GRIA1 | |
| SCHEMBL2021837 | 0.72 | ZAP70 (0.40) | — | |
| SCHEMBL2020203 | 0.72 | ZAP70 (0.33) | GRIA1 | |
| SCHEMBL2021662 | 0.72 | ADORA3 (0.40) | ADORA3 | |
| SCHEMBL2023129 | 0.71 | ZAP70 (0.34) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110160215-A1 | Substituted Triazolo-Pyrazine Compounds | ARQULE, INC. (US) | 2011-06-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110160215-A1 | Substituted Triazolo-Pyrazine Compounds | MKI67, TP53, THPO | ADORA3 1835/4885HCAR3 1603/4885GRIA1 2924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.