Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ATP4A | P20648 | 2/20 | 0.31 |
| ▸ | ATP4B | P51164 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16535518 | 0.86 | LMNA (0.33) | LMNAMAPTRXFP1 | |
| SCHEMBL20197471 | 0.83 | C1S (0.35) | LMNAMAPTRXFP1 | |
| SCHEMBL22152727 | 0.74 | SREBF2 (0.43) | LMNAMAPT | |
| SCHEMBL16535326 | 0.71 | LMNA (0.32) | LMNAMAPTRXFP1 | |
| SCHEMBL20197220 | 0.71 | SREBF2 (0.35) | LMNAMAPTRXFP1 | |
| SCHEMBL20197267 | 0.70 | C1S (0.34) | LMNAMAPTRXFP1 | |
| SCHEMBL20197278 | 0.70 | CNR2 (0.39) | LMNAMAPTRXFP1 | |
| SCHEMBL20197221 | 0.70 | SREBF2 (0.55) | LMNAMAPT | |
| SCHEMBL20197297 | 0.70 | CYP19A1 (0.35) | LMNAMAPTRXFP1 | |
| SCHEMBL20197302 | 0.70 | SMN1; SMN2 (0.46) | LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |