Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.31 |
| ▸ | C1S | P09871 | 1/20 | 0.31 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16535630 | 0.84 | KDM1A (0.34) | MAPTLMNARXFP1ALDH1A1 | |
| SCHEMBL22152727 | 0.77 | SREBF2 (0.43) | MAPTLMNAALDH1A1 | |
| SCHEMBL16536557 | 0.75 | KDM1A (0.35) | SMN1; SMN2MAPTLMNARXFP1ALDH1A1 | |
| SCHEMBL20197471 | 0.74 | C1S (0.35) | SMN1; SMN2MAPTLMNARXFP1CYP1B1 | |
| SCHEMBL20197203 | 0.74 | KDM4E (0.36) | SMN1; SMN2MAPTLMNARXFP1MEN1 | |
| SCHEMBL20197302 | 0.74 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTLMNACYP1B1CYP1A2 | |
| SCHEMBL20197336 | 0.74 | CYP19A1 (0.46) | SMN1; SMN2MAPTLMNACYP1B1CYP1A2 | |
| SCHEMBL20197228 | 0.73 | CYP1A1 (0.42) | SMN1; SMN2MAPTLMNACYP1B1CYP1A2 | |
| SCHEMBL20197472 | 0.73 | CYP1B1 (0.36) | SMN1; SMN2MAPTLMNARXFP1CYP1B1 | |
| SCHEMBL20197219 | 0.72 | SREBF2 (0.33) | MAPTLMNARXFP1C1S |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |