Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | EIF4E | P06730 | 3/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.40 |
| ▸ | C1S | P09871 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | CRHBP | P24387 | 1/20 | 0.35 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | PDE2A | O00408 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16535642 | 0.82 | PTGS1 (0.49) | CYP19A1EIF4ECYP17A1RAB9AKMT2A | |
| SCHEMBL20197302 | 0.82 | SMN1; SMN2 (0.46) | EIF4ERAB9AKMT2AMEN1NPC1 | |
| SCHEMBL20197440 | 0.80 | KDM4E (0.36) | CYP19A1EIF4EC1SRAB9AKMT2A | |
| SCHEMBL20197243 | 0.80 | NUDT1 (0.45) | CYP19A1 | |
| SCHEMBL20197318 | 0.79 | EIF4E (0.46) | EIF4EC1SRAB9ANPC1SMN1; SMN2 | |
| SCHEMBL20197228 | 0.79 | CYP1A1 (0.42) | CYP19A1EIF4EC1SRAB9AKMT2A | |
| SCHEMBL20197240 | 0.78 | ALDH1A1 (0.53) | EIF4ERAB9AKMT2AMEN1NPC1 | |
| SCHEMBL20197342 | 0.78 | LMNA (0.37) | C1SRAB9AKMT2AMEN1NPC1 | |
| SCHEMBL20197221 | 0.78 | SREBF2 (0.55) | KDM4EMAPTL3MBTL1LMNA | |
| SCHEMBL22152727 | 0.77 | SREBF2 (0.43) | KDM4EMAPTL3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |