Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKD1 | Q15139 | 7/20 | 0.39 |
| ▸ | PRKD2 | Q9BZL6 | 4/20 | 0.39 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | MAPK14 | Q16539 | 8/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | PRKCI | P41743 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16535875 | 0.84 | PRKD1 (0.38) | PRKD1PRKD2CDC7MAPK14KDM4E | |
| SCHEMBL20197440 | 0.80 | KDM4E (0.36) | KDM4E | |
| SCHEMBL20197350 | 0.78 | PIM1 (0.41) | KDM4EL3MBTL1 | |
| SCHEMBL20197302 | 0.78 | SMN1; SMN2 (0.46) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL20197232 | 0.78 | EIF4E (0.43) | KDM4ETYR | |
| SCHEMBL20197249 | 0.78 | SREBF2 (0.43) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL20197221 | 0.78 | SREBF2 (0.55) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL20197309 | 0.77 | CYP1B1 (0.41) | KDM4EALDH1A1 | |
| SCHEMBL22152727 | 0.77 | SREBF2 (0.43) | KDM4EALDH1A1L3MBTL1 | |
| SCHEMBL20197320 | 0.76 | SREBF2 (0.44) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |