Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EIF4E | P06730 | 13/20 | 0.43 |
| ▸ | CNR1 | P21554 | 4/20 | 0.40 |
| ▸ | TYR | P14679 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20197276 | 0.96 | EIF4E (0.45) | EIF4ENPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL16536194 | 0.87 | EIF4E (0.43) | EIF4ECNR1TYRNPC1RAB9A | |
| SCHEMBL16535952 | 0.83 | EIF4E (0.45) | EIF4ENPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL20197306 | 0.78 | PRKD1 (0.39) | TYRKDM4E | |
| SCHEMBL20197340 | 0.76 | EIF4E (0.53) | EIF4ECNR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20197302 | 0.73 | SMN1; SMN2 (0.46) | EIF4ENPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL20197309 | 0.72 | CYP1B1 (0.41) | EIF4ECNR1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL20197240 | 0.72 | ALDH1A1 (0.53) | EIF4ENPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL20197440 | 0.70 | KDM4E (0.36) | EIF4ENPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL20197318 | 0.69 | EIF4E (0.46) | EIF4ENPC1RAB9ASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |