SCHEMBL5609022

SCHEMBL5609022

CCCCCCNc1cccc(C)c1

nearest known ligand 0.69

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.69
CYP1A2 P05177 1/20 0.69
CYP3A4 P08684 1/20 0.69
CYP2D6 P10635 1/20 0.69
CYP2C9 P11712 1/20 0.69
CYP2C19 P33261 1/20 0.69
HTT P42858 1/20 0.69
ABL1 P00519 1/20 0.51
HPGD P15428 1/20 0.45
KCNH3 Q9ULD8 1/20 0.45
HDAC1 Q13547 1/20 0.45
NPSR1 Q6W5P4 1/20 0.44
PLK1 P53350 3/20 0.44
EPHX1 P07099 3/20 0.43
ICMT O60725 1/20 0.43
F2R P25116 1/20 0.43
GFER P55789 1/20 0.42
HDAC11 Q96DB2 1/20 0.42
HDAC8 Q9BY41 1/20 0.42
ADRA2A P08913 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15231967 1.00 MAPT (0.69) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL9116266 1.00 MAPT (0.69) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL5597408 1.00 MAPT (0.69) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL29565935 1.00 MAPT (0.69) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL15229858 1.00 MAPT (0.69) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL15230385 1.00 MAPT (0.69) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL20197373 0.98 MAPT (0.71) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL3440754 0.93 MAPT (0.74) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL31519377 0.93 MAPT (0.74) MAPTCYP1A2CYP3A4CYP2D6CYP2C9
SCHEMBL3662823 0.87 ABL1 (0.54) MAPTCYP1A2CYP3A4CYP2D6CYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3396028-B1 DIRECT ELECTROCHEMICAL SYNTHESIS OF DOPED CONDUCTIVE POLYMERS ON METAL ALLOYS BOEING CO (US) 2022-04-06 EP claimed
EP-1428857-B1 Process to make a conductive composition of a fluorinated polymer which contains polyaniline ARKEMA FRANCE (FR) 2007-01-31 EP claimed
US-5415893-A Dispersion of electrically conductive particles in a dispersing medium DSM N.V. (NL) 1995-05-16 US claimed
EP-3396028-B1 DIRECT ELECTROCHEMICAL SYNTHESIS OF DOPED CONDUCTIVE POLYMERS ON METAL ALLOYS BOEING CO (US) 2022-04-06 EP disclosed
CN-107922428-B Thienopyrrole compounds and their use as inhibitors of oplophorus-derived luciferase 普洛麦格公司 2021-02-05 CN disclosed
EP-3313846-B1 THIENOPYRROLE COMPOUNDS AND USES THEREOF AS INHIBITORS OF OPLOPHORUS-DERIVED LUCIFERASES PROMEGA CORP (US) 2020-05-06 EP disclosed
US-20200063110-A1 THIENOPYRROLE COMPOUNDS AND USES THEREOF PROMEGA CORPORATION 2020-02-27 US disclosed
US-10557210-B2 Direct electrochemical synthesis of doped conductive polymers on metal alloys THE BOEING COMPANY (US) 2020-02-11 US disclosed
EP-3396028-A2 DIRECT ELECTROCHEMICAL SYNTHESIS OF DOPED CONDUCTIVE POLYMERS ON METAL ALLOYS The Boeing Company (US) 2018-10-31 EP disclosed
EP-3313846-A1 THIENOPYRROLE COMPOUNDS AND USES THEREOF AS INHIBITORS OF OPLOPHORUS-DERIVED LUCIFERASES Promega Corporation (US) 2018-05-02 EP disclosed
CN-107922428-A Thienopyrroles compound and its purposes as the inhibitor for piercing shrimp source property luciferase 普洛麦格公司 2018-04-17 CN disclosed
EP-0821040-A1 Aqueous coating dispersion, process for the preparation thereof and use thereof in anticorrosive paint DSM N.V. (NL) 1998-01-28 EP disclosed
EP-0538939-B1 Polymer composition DSM NV (NL) 1996-06-19 EP disclosed
US-5415893-A Dispersion of electrically conductive particles in a dispersing medium DSM N.V. (NL) 1995-05-16 US disclosed
US-5338413-A Method for the preparation of a polymeric shaped article containing an electrically conductive polymer DSM N.V. (NL) 1994-08-16 US disclosed
EP-0589529-A1 Dispersion of electrically conductive particles in a dispersing medium DSM N.V. (NL) 1994-03-30 EP disclosed
EP-0587204-A1 Method for the preparation of a polymeric shaped article containing an electrically conductive polymer DSM N.V. (NL) 1994-03-16 EP disclosed
US-5262483-A Styrene-maleic anhydride and polyaniline grafted with processability and conductivity DSM N.V. (NL) 1993-11-16 US disclosed
EP-0538939-A1 Polymer composition DSM N.V. (NL) 1993-04-28 EP disclosed
EP-0415123-A2 1-Phenylalkyl-3-phenylurea derivatives Mitsubishi Chemical Corporation (JP) 1991-03-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200063110-A1 THIENOPYRROLE COMPOUNDS AND USES THEREOF THOP1, TYMP, CREBBP MAPT 2973/4885CYP1A2 1142/4885CYP3A4 873/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.