SCHEMBL2019743

SCHEMBL2019743

COC(OC)[SiH2]CN=C=S

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.36
MIF P14174 2/20 0.31
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2772743 0.80 NAAA (0.33) TRPA1
SCHEMBL580369 0.77
SCHEMBL2027290 0.75 NAAA (0.41) TRPA1MIF
SCHEMBL881511 0.64
SCHEMBL310298 0.63
SCHEMBL331418 0.63
SCHEMBL15334085 0.61
SCHEMBL3953647 0.61
SCHEMBL1162765 0.59
SCHEMBL5419238 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103524714-B As the silane compound/carbamide compound of the heat-activatable solidifying agent for composition epoxy resin SIKA TECHNOLOGY AG (CH) 2016-04-06 CN disclosed
US-9284447-B2 Silane/urea compound as a heat-activated curing agent for epoxide resin compositions SIKA TECHNOLOGY AG (CH) 2016-03-15 US disclosed
US-20140216655-A1 SILANE/UREA COMPOUND AS A HEAT-ACTIVATED CURING AGENT FOR EPOXIDE RESIN COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2014-08-07 US disclosed
US-8728271-B2 Silane/urea compound as a heat-activatable curing agent for epoxide resin compositions SIKA TECHNOLOGY AG (CH) 2014-05-20 US disclosed
CN-102131817-B Silane/urea compounds as heat-activatable curing agents for epoxy resin compositions SIKA TECHNOLOGY AG 2014-05-07 CN disclosed
CN-103524714-A Silane/urea compound as heat-activatable curing agent for epoxide resin compositions SIKA TECHNOLOGY AG 2014-01-22 CN disclosed
CN-102131817-A Silane/urea compounds as heat-activatable curing agents for epoxy resin compositions SIKA TECHNOLOGY AG 2011-07-20 CN disclosed
US-20110155320-A1 SILANE/UREA COMPOUND AS A HEAT-ACTIVATABLE CURING AGENT FOR EPOXIDE RESIN COMPOSITIONS SIKA TECHNOLOGY AG (CH) 2011-06-30 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110155320-A1 SILANE/UREA COMPOUND AS A HEAT-ACTIVATABLE CURING AGENT FOR EPOXIDE RESIN COMPOSITIONS SEM1, UBA1, UBA3 TRPA1 2333/4885MIF 3452/4885CYP3A4 1726/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.