Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | C1S | P09871 | 1/20 | 0.39 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | TEK | Q02763 | 1/20 | 0.34 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.34 |
| ▸ | EGFR | P00533 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | CRHBP | P24387 | 1/20 | 0.33 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.33 |
| ▸ | EIF4E | P06730 | 2/20 | 0.33 |
| ▸ | PGK1 | P00558 | 1/20 | 0.32 |
| ▸ | IGF1R | P08069 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20197337 | 0.84 | CYP1A2 (0.40) | C1SCYP1A1CYP1B1CYP1A2CYP19A1 | |
| SCHEMBL16535825 | 0.81 | KDM1A (0.39) | C1SCYP1A1CYP1B1CYP1A2CYP19A1 | |
| SCHEMBL20197238 | 0.80 | CYP19A1 (0.44) | CYP19A1AMY1AKDM4ENPC1RAB9A | |
| SCHEMBL20197304 | 0.78 | CDK2 (0.39) | C1SCYP1A1CYP1B1CYP1A2CYP19A1 | |
| SCHEMBL20197479 | 0.78 | EIF4E (0.39) | CYP1A2MAPTKDM4ENPC1RAB9A | |
| SCHEMBL20197235 | 0.76 | SREBF2 (0.42) | MAPTKDM4E | |
| SCHEMBL20197481 | 0.76 | EIF4E (0.37) | KDM4ENPC1RAB9ASMN1; SMN2CRHBP | |
| SCHEMBL20197159 | 0.76 | CYP19A1 (0.33) | CYP1A1CYP1B1CYP1A2CYP19A1AMY1A | |
| SCHEMBL20197301 | 0.74 | KDM4E (0.34) | C1SCYP19A1MAPTKDM4ENPC1 | |
| SCHEMBL20197223 | 0.74 | SREBF2 (0.42) | MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |