Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 6/20 | 0.39 |
| ▸ | CDC7 | O00311 | 5/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 5/20 | 0.39 |
| ▸ | DBF4 | Q9UBU7 | 5/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 3/20 | 0.39 |
| ▸ | CDK9 | P50750 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.39 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.39 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.39 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.39 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.39 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 2/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.37 |
| ▸ | MALT1 | Q9UDY8 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20197238 | 0.84 | CYP19A1 (0.44) | KDM4ENPC1RAB9AAMY1ACYP19A1 | |
| SCHEMBL16535320 | 0.80 | CDC7 (0.39) | CDK2CDC7CCNE1DBF4CCNT1 | |
| SCHEMBL20197159 | 0.80 | CYP19A1 (0.33) | KDM4ENPC1RAB9AAMY1ACYP19A1 | |
| SCHEMBL20197204 | 0.80 | ATP4A (0.33) | MAPT | |
| SCHEMBL20197337 | 0.79 | CYP1A2 (0.40) | KDM4ENPC1RAB9AMAPTCYP19A1 | |
| SCHEMBL20197301 | 0.79 | KDM4E (0.34) | KDM4ENPC1RAB9AMAPTCYP19A1 | |
| SCHEMBL20197235 | 0.79 | SREBF2 (0.42) | KDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL20197443 | 0.78 | C1S (0.39) | KDM4ENPC1RAB9AMAPTAMY1A | |
| SCHEMBL20197223 | 0.78 | SREBF2 (0.42) | KDM4EMAPTL3MBTL1ALDH1A1 | |
| SCHEMBL20197368 | 0.78 | MAPK14 (0.35) | CDK2KDM4ENPC1RAB9ACYP1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3038622-B1 | HETEROCYCLIC COMPOUNDS AND METHODS OF USE | MEDIVATION TECH LLC (US) | 2018-05-30 | — | — | EP | disclosed |